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Distinct stromal and immune cell interactions shape the pathogenesis of rheumatoid and psoriatic arthritis.
Floudas A, Smith CM, Tynan O, Neto N, Krishna V, Wade SM, Hanlon M, Cunningham C, Marzaioli V, Canavan M, Fletcher JM, Mullan RH, Cole S, Hao LY, Monaghan MG, Nagpal S, Veale DJ, Fearon U. Floudas A, et al. Among authors: smith cm. Ann Rheum Dis. 2022 Aug 11;81(9):1224-1242. doi: 10.1136/annrheumdis-2021-221761. Ann Rheum Dis. 2022. PMID: 35701153 Free article.
Targeting the NLRP3 inflammasome reduces inflammation in hidradenitis suppurativa skin.
Moran B, Smith CM, Zaborowski A, Ryan M, Karman J, Dunstan RW, Smith KM, Hambly R, Musilova J, Petrasca A, Fabre A, O'Donnell M, Hokamp K, Mills KHG, Housley WJ, Winter DC, Kirby B, Fletcher JM. Moran B, et al. Among authors: smith km, smith cm. Br J Dermatol. 2023 Sep 15;189(4):447-458. doi: 10.1093/bjd/ljad184. Br J Dermatol. 2023. PMID: 37243544
Metformin has anti-inflammatory effects and induces immunometabolic reprogramming via multiple mechanisms in hidradenitis suppurativa.
Petrasca A, Hambly R, Kearney N, Smith CM, Pender EK, Mac Mahon J, O'Rourke AM, Ismaiel M, Boland PA, Almeida JP, Kennedy C, Zaborowski A, Murphy S, Winter D, Kirby B, Fletcher JM. Petrasca A, et al. Among authors: smith cm. Br J Dermatol. 2023 Nov 16;189(6):730-740. doi: 10.1093/bjd/ljad305. Br J Dermatol. 2023. PMID: 37648653
Loss of synovial tissue macrophage homeostasis precedes rheumatoid arthritis clinical onset.
Hanlon MM, Smith CM, Canavan M, Neto NGB, Song Q, Lewis MJ, O'Rourke AM, Tynan O, Barker BE, Gallagher P, Mullan R, Hurson C, Moran B, Monaghan MG, Pitzalis C, Fletcher JM, Nagpal S, Veale DJ, Fearon U. Hanlon MM, et al. Among authors: smith cm. Sci Adv. 2024 Sep 27;10(39):eadj1252. doi: 10.1126/sciadv.adj1252. Epub 2024 Sep 25. Sci Adv. 2024. PMID: 39321281 Free PMC article.
1,299 results