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Cholesterol binding to VCAM-1 promotes vascular inflammation.
bioRxiv [Preprint]. 2024 Sep 18:2024.09.17.613543. doi: 10.1101/2024.09.17.613543.
bioRxiv. 2024.
PMID: 39345495
Free PMC article.
Preprint.
Adipogenin Dictates Adipose Tissue Expansion by Facilitating the Assembly of a Dodecameric Seipin Complex.
Li C, Sun XN, Funcke JB, Vanharanta L, Joffin N, Li Y, Prasanna X, Paredes M, Joung C, Gordillo R, Vörös C, Kulig W, Straub L, Chen S, Velasco J, Cobb A, Padula D, Wang MY, Onodera T, Varlamov O, Li Y, Liu C, Nawrocki AR, Zhao S, Oh DY, Wang ZV, Goodman JM, Wynn RM, Vattulainen I, Han Y, Ikonen E, Scherer PE.
Li C, et al. Among authors: vanharanta l.
bioRxiv [Preprint]. 2024 Jul 26:2024.07.25.605195. doi: 10.1101/2024.07.25.605195.
bioRxiv. 2024.
PMID: 39211078
Free PMC article.
Preprint.
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Cholesterol esters form supercooled lipid droplets whose nucleation is facilitated by triacylglycerols.
Dumesnil C, Vanharanta L, Prasanna X, Omrane M, Carpentier M, Bhapkar A, Enkavi G, Salo VT, Vattulainen I, Ikonen E, Thiam AR.
Dumesnil C, et al. Among authors: vanharanta l.
Nat Commun. 2023 Feb 17;14(1):915. doi: 10.1038/s41467-023-36375-6.
Nat Commun. 2023.
PMID: 36807572
Free PMC article.
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ORP2 couples LDL-cholesterol transport to FAK activation by endosomal cholesterol/PI(4,5)P2 exchange.
Takahashi K, Kanerva K, Vanharanta L, Almeida-Souza L, Lietha D, Olkkonen VM, Ikonen E.
Takahashi K, et al. Among authors: vanharanta l.
EMBO J. 2021 Jul 15;40(14):e106871. doi: 10.15252/embj.2020106871. Epub 2021 Jun 14.
EMBO J. 2021.
PMID: 34124795
Free PMC article.
Item in Clipboard
High-content imaging and structure-based predictions reveal functional differences between Niemann-Pick C1 variants.
Vanharanta L, Peränen J, Pfisterer SG, Enkavi G, Vattulainen I, Ikonen E.
Vanharanta L, et al.
Traffic. 2020 May;21(5):386-397. doi: 10.1111/tra.12727. Epub 2020 Apr 5.
Traffic. 2020.
PMID: 32144825
Free article.
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HSP70 induces liver X receptor pathway activation and cholesterol reduction in vitro and in vivo.
Gungor B, Vanharanta L, Hölttä-Vuori M, Pirhonen J, Petersen NHT, Gramolelli S, Ojala PM, Kirkegaard T, Ikonen E.
Gungor B, et al. Among authors: vanharanta l.
Mol Metab. 2019 Oct;28:135-143. doi: 10.1016/j.molmet.2019.07.005. Epub 2019 Jul 6.
Mol Metab. 2019.
PMID: 31327756
Free PMC article.
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