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Page 1
Mechanism of disease and therapeutic rescue of Dok7 congenital myasthenia.
Oury J, Zhang W, Leloup N, Koide A, Corrado AD, Ketavarapu G, Hattori T, Koide S, Burden SJ. Oury J, et al. Among authors: ketavarapu g. Nature. 2021 Jul;595(7867):404-408. doi: 10.1038/s41586-021-03672-3. Epub 2021 Jun 23. Nature. 2021. PMID: 34163073 Free PMC article.
Monobody adapter for functional antibody display on nanoparticles for adaptable targeted delivery applications.
Albert C, Bracaglia L, Koide A, DiRito J, Lysyy T, Harkins L, Edwards C, Richfield O, Grundler J, Zhou K, Denbaum E, Ketavarapu G, Hattori T, Perincheri S, Langford J, Feizi A, Haakinson D, Hosgood SA, Nicholson ML, Pober JS, Saltzman WM, Koide S, Tietjen GT. Albert C, et al. Among authors: ketavarapu g. Nat Commun. 2022 Oct 11;13(1):5998. doi: 10.1038/s41467-022-33490-8. Nat Commun. 2022. PMID: 36220817 Free PMC article.
Exploring switch II pocket conformation of KRAS(G12D) with mutant-selective monobody inhibitors.
Akkapeddi P, Hattori T, Khan I, Glasser E, Koide A, Ketavarapu G, Whaby M, Zuberi M, Teng KW, Lefler J, Maso L, Bang I, Ostrowski MC, O'Bryan JP, Koide S. Akkapeddi P, et al. Among authors: ketavarapu g. Proc Natl Acad Sci U S A. 2023 Jul 11;120(28):e2302485120. doi: 10.1073/pnas.2302485120. Epub 2023 Jul 3. Proc Natl Acad Sci U S A. 2023. PMID: 37399416 Free PMC article.
Inhibition and degradation of NRAS with a pan-NRAS monobody.
Whaby M, Ketavarapu G, Koide A, Mazzei M, Mintoo M, Glasser E, Patel U, Nasarre C, Sale MJ, McCormick F, Koide S, O'Bryan JP. Whaby M, et al. Among authors: ketavarapu g. Oncogene. 2024 Nov;43(48):3489-3497. doi: 10.1038/s41388-024-03186-y. Epub 2024 Oct 8. Oncogene. 2024. PMID: 39379700 Free PMC article.