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Multitarget-Directed Gallium(III) Tris(acyl-pyrazolonate) Complexes Induce Ferroptosis in Cancer Cells via Dysregulation of Cell Redox Homeostasis and Inhibition of the Mevalonate Pathway.
Romani D, Marchetti F, Di Nicola C, Cuccioloni M, Gong C, Eleuteri AM, Galindo A, Fadaei-Tirani F, Nabissi M, Pettinari R. Romani D, et al. Among authors: di nicola c. J Med Chem. 2023 Mar 9;66(5):3212-3225. doi: 10.1021/acs.jmedchem.2c01374. Epub 2023 Feb 21. J Med Chem. 2023. PMID: 36802330 Free PMC article.
New RuII (arene) complexes with halogen-substituted bis- and tris(pyrazol-1-yl)borate ligands.
Orbisaglia S, Di Nicola C, Marchetti F, Pettinari C, Pettinari R, Martins LM, Alegria EC, da Silva MF, Rocha BG, Kuznetsov ML, Pombeiro AJ, Skelton BW, Sobolev AN, White AH. Orbisaglia S, et al. Among authors: di nicola c. Chemistry. 2014 Mar 24;20(13):3689-704. doi: 10.1002/chem.201304406. Epub 2014 Feb 24. Chemistry. 2014. PMID: 24616192
Ligand Design for N, O- or N, N-Pyrazolone-Based Hydrazones Ruthenium(II)-Arene Complexes and Investigation of Their Anticancer Activity.
Pettinari R, Marchetti F, Di Nicola C, Pettinari C, Galindo A, Petrelli R, Cappellacci L, Cuccioloni M, Bonfili L, Eleuteri AM, Guedes da Silva MFC, Pombeiro AJL. Pettinari R, et al. Among authors: di nicola c. Inorg Chem. 2018 Nov 19;57(22):14123-14133. doi: 10.1021/acs.inorgchem.8b01935. Epub 2018 Oct 26. Inorg Chem. 2018. PMID: 30362721
Evaluation of anticancer role of a novel ruthenium(II)-based compound compared with NAMI-A and cisplatin in impairing mitochondrial functionality and promoting oxidative stress in triple negative breast cancer models.
Silvestri S, Cirilli I, Marcheggiani F, Dludla P, Lupidi G, Pettinari R, Marchetti F, Di Nicola C, Falcioni G, Marchini C, Orlando P, Tiano L, Amici A. Silvestri S, et al. Among authors: di nicola c. Mitochondrion. 2021 Jan;56:25-34. doi: 10.1016/j.mito.2020.11.004. Epub 2020 Nov 19. Mitochondrion. 2021. PMID: 33220497
Zinc(II) Complex with Pyrazolone-Based Hydrazones is Strongly Effective against Trypanosoma brucei Which Causes African Sleeping Sickness.
Marchetti F, Tombesi A, Di Nicola C, Pettinari R, Verdicchio F, Crispini A, Scarpelli F, Baldassarri C, Marangoni E, Hofer A, Galindo A, Petrelli R. Marchetti F, et al. Among authors: di nicola c. Inorg Chem. 2022 Aug 29;61(34):13561-13575. doi: 10.1021/acs.inorgchem.2c02201. Epub 2022 Aug 15. Inorg Chem. 2022. PMID: 35969809 Free PMC article.
32 results