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Inducing vulnerability to InhA inhibition restores isoniazid susceptibility in drug resistant Mycobacterium tuberculosis.
Harrison GA, Cho K, Wang ER, Sarkar S, Almqvist F, Patti GJ, Stallings CL. Harrison GA, et al. Among authors: wang er. bioRxiv [Preprint]. 2023 Feb 7:2023.02.06.527416. doi: 10.1101/2023.02.06.527416. bioRxiv. 2023. Update in: mBio. 2024 Mar 13;15(3):e0296823. doi: 10.1128/mbio.02968-23 PMID: 36798348 Free PMC article. Updated. Preprint.
Design, Synthesis, and Evaluation of Novel Δ2-Thiazolino 2-Pyridone Derivatives That Potentiate Isoniazid Activity in an Isoniazid-Resistant Mycobacterium tuberculosis Mutant.
Sarkar S, Mayer Bridwell AE, Good JAD, Wang ER, McKee SR, Valenta J, Harrison GA, Flentie KN, Henry FL, Wixe T, Demirel P, Vagolu SK, Chatagnon J, Machelart A, Brodin P, Tønjum T, Stallings CL, Almqvist F. Sarkar S, et al. Among authors: wang er. J Med Chem. 2023 Aug 24;66(16):11056-11077. doi: 10.1021/acs.jmedchem.3c00358. Epub 2023 Jul 24. J Med Chem. 2023. PMID: 37485869 Free PMC article.
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