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Adipocyte autophagy limits gut inflammation by controlling oxylipin and IL-10.
Richter FC, Friedrich M, Kampschulte N, Piletic K, Alsaleh G, Zummach R, Hecker J, Pohin M, Ilott N, Guschina I, Wideman SK, Johnson E, Borsa M, Hahn P, Morriseau C, Hammock BD, Schipper HS, Edwards CM, Zechner R, Siegmund B, Weidinger C, Schebb NH, Powrie F, Simon AK. Richter FC, et al. Among authors: powrie f. EMBO J. 2023 Mar 15;42(6):e112202. doi: 10.15252/embj.2022112202. Epub 2023 Feb 16. EMBO J. 2023. PMID: 36795015 Free PMC article.
Alpha kinase 1 controls intestinal inflammation by suppressing the IL-12/Th1 axis.
Ryzhakov G, West NR, Franchini F, Clare S, Ilott NE, Sansom SN, Bullers SJ, Pearson C, Costain A, Vaughan-Jackson A, Goettel JA, Ermann J, Horwitz BH, Buti L, Lu X, Mukhopadhyay S, Snapper SB, Powrie F. Ryzhakov G, et al. Among authors: powrie f. Nat Commun. 2018 Sep 18;9(1):3797. doi: 10.1038/s41467-018-06085-5. Nat Commun. 2018. PMID: 30228258 Free PMC article.
The Short Chain Fatty Acid Butyrate Imprints an Antimicrobial Program in Macrophages.
Schulthess J, Pandey S, Capitani M, Rue-Albrecht KC, Arnold I, Franchini F, Chomka A, Ilott NE, Johnston DGW, Pires E, McCullagh J, Sansom SN, Arancibia-Cárcamo CV, Uhlig HH, Powrie F. Schulthess J, et al. Among authors: powrie f. Immunity. 2019 Feb 19;50(2):432-445.e7. doi: 10.1016/j.immuni.2018.12.018. Epub 2019 Jan 23. Immunity. 2019. PMID: 30683619 Free PMC article.
Deconvolution of monocyte responses in inflammatory bowel disease reveals an IL-1 cytokine network that regulates IL-23 in genetic and acquired IL-10 resistance.
Aschenbrenner D, Quaranta M, Banerjee S, Ilott N, Jansen J, Steere B, Chen YH, Ho S, Cox K, Arancibia-Cárcamo CV, Coles M, Gaffney E, Travis SP, Denson L, Kugathasan S, Schmitz J, Powrie F, Sansom SN, Uhlig HH. Aschenbrenner D, et al. Among authors: powrie f. Gut. 2021 Jun;70(6):1023-1036. doi: 10.1136/gutjnl-2020-321731. Epub 2020 Oct 9. Gut. 2021. PMID: 33037057 Free PMC article.
209 results