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Phase I study of CD19 CAR T-cell therapy harboring a fully human scFv in CAR-naïve adult B-ALL patients.
Gauthier J, Liang EC, Huang JJ, Kimble EL, Hirayama AV, Fiorenza S, Voutsinas JM, Wu QV, Jaeger-Ruckstuhl CA, Pender BS, Kirchmeier DR, Torkelson A, Braathen K, Basom R, Shadman M, Kopmar NE, Cassaday RD, Riddell SR, Maloney DG, Turtle CJ. Gauthier J, et al. Among authors: maloney dg. Blood Adv. 2025 Jan 16:bloodadvances.2024015314. doi: 10.1182/bloodadvances.2024015314. Online ahead of print. Blood Adv. 2025. PMID: 39820359
Development and validation of predictive models of early immune effector cell-associated hematotoxicity (eIPMs).
Liang EC, Huang JJ, Portuguese AJ, Ortiz-Maldonado V, Albittar A, Wuliji N, Basom R, Jeon Y, Wu QV, Torkelson A, Kirchmeier DR, Chutnik A, Pender BS, Sorror ML, Hill JA, Kopmar NE, Banerjee R, Cowan AJ, Green DJ, Gopal AK, Poh C, Shadman M, Hirayama AV, Till BG, Kimble EL, Iovino L, Chapuis AG, Otegbeye F, Cassaday RD, Milano F, Turtle CJ, Maloney DG, Gauthier J. Liang EC, et al. Among authors: maloney dg. Blood Adv. 2024 Dec 3:bloodadvances.2024014455. doi: 10.1182/bloodadvances.2024014455. Online ahead of print. Blood Adv. 2024. PMID: 39626349
12-Lipoxygenase inhibition delays onset of autoimmune diabetes in human gene replacement mice.
Nargis T, Muralidharan C, Enriquez JR, Wang JE, Kaylan KB, Chakraborty A, Pratuangtham S, Figatner K, Nelson JB, May SC, Nadler JL, Boxer MB, Maloney DJ, Tersey SA, Mirmira RG. Nargis T, et al. Among authors: maloney dj. JCI Insight. 2024 Dec 20;9(24):e185299. doi: 10.1172/jci.insight.185299. JCI Insight. 2024. PMID: 39531315 Free PMC article.
Phase 1 Study of ROR1 Specific CAR T Cells in Advanced Hematopoietic and Epithelial Malignancies.
Jaeger-Ruckstuhl CA, Specht JM, Voutsinas JM, MacMillan HR, Wu QV, Muhunthan V, Berger C, Pullarkat S, Wright JH, Yeung CCS, Hyun TS, Seaton B, Aicher LD, Song X, Pierce RH, Lo Y, Cole GO, Lee SM, Newell EW, Maloney DG, Riddell SR. Jaeger-Ruckstuhl CA, et al. Among authors: maloney dg. Clin Cancer Res. 2024 Oct 28. doi: 10.1158/1078-0432.CCR-24-2172. Online ahead of print. Clin Cancer Res. 2024. PMID: 39466024
Histone marks identify novel transcription factors that parse CAR-T subset-of-origin, clinical potential and expansion.
Fiorenza S, Zheng Y, Purushe J, Bock TJ, Sarthy J, Janssens DH, Sheih AS, Kimble EL, Kirchmeier D, Phi TD, Gauthier J, Hirayama AV, Riddell SR, Wu Q, Gottardo R, Maloney DG, Yang JYH, Henikoff S, Turtle CJ. Fiorenza S, et al. Among authors: maloney dg. Nat Commun. 2024 Sep 27;15(1):8309. doi: 10.1038/s41467-024-52503-2. Nat Commun. 2024. PMID: 39333103 Free PMC article.
Detection of circulating tumor DNA by tumor-informed whole-genome sequencing enables prediction of recurrence in stage III colorectal cancer patients.
Frydendahl A, Nors J, Rasmussen MH, Henriksen TV, Nesic M, Reinert T, Afterman D, Lauterman T, Kuzman M, Gonzalez S, Glavas D, Smadback J, Maloney D, Levativ J, Yahalom M, Ptashkin R, Tavassoly I, Donenhirsh Z, White E, Kandasamy R, Alon U, Nordentoft I, Lindskrog SV, Dyrskjøt L, Jaensch C, Løve US, Andersen PV, Thorlacius-Ussing O, Iversen LH, Gotschalck KA, Zviran A, Oklander B, Andersen CL. Frydendahl A, et al. Among authors: maloney d. Eur J Cancer. 2024 Nov;211:114314. doi: 10.1016/j.ejca.2024.114314. Epub 2024 Sep 11. Eur J Cancer. 2024. PMID: 39316995 Free article.
880 results