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Page 1
Toxicity modelling of Plk1-targeted therapies in genetically engineered mice and cultured primary mammalian cells.
Raab M, Kappel S, Krämer A, Sanhaji M, Matthess Y, Kurunci-Csacsko E, Calzada-Wack J, Rathkolb B, Rozman J, Adler T, Busch DH, Esposito I, Fuchs H, Gailus-Durner V, Klingenspor M, Wolf E, Sänger N, Prinz F, Angelis MH, Seibler J, Yuan J, Bergmann M, Knecht R, Kreft B, Strebhardt K. Raab M, et al. Among authors: rathkolb b. Nat Commun. 2011 Jul 19;2:395. doi: 10.1038/ncomms1395. Nat Commun. 2011. PMID: 21772266 Free PMC article.
Clinical chemistry of human FcRn transgenic mice.
Stein C, Kling L, Proetzel G, Roopenian DC, de Angelis MH, Wolf E, Rathkolb B. Stein C, et al. Among authors: rathkolb b. Mamm Genome. 2012 Apr;23(3-4):259-69. doi: 10.1007/s00335-011-9379-6. Epub 2011 Dec 23. Mamm Genome. 2012. PMID: 22193411
Neurobeachin, a regulator of synaptic protein targeting, is associated with body fat mass and feeding behavior in mice and body-mass index in humans.
Olszewski PK, Rozman J, Jacobsson JA, Rathkolb B, Strömberg S, Hans W, Klockars A, Alsiö J, Risérus U, Becker L, Hölter SM, Elvert R, Ehrhardt N, Gailus-Durner V, Fuchs H, Fredriksson R, Wolf E, Klopstock T, Wurst W, Levine AS, Marcus C, de Angelis MH, Klingenspor M, Schiöth HB, Kilimann MW. Olszewski PK, et al. Among authors: rathkolb b. PLoS Genet. 2012;8(3):e1002568. doi: 10.1371/journal.pgen.1002568. Epub 2012 Mar 15. PLoS Genet. 2012. PMID: 22438821 Free PMC article.
A novel N-ethyl-N-nitrosourea-induced mutation in phospholipase Cγ2 causes inflammatory arthritis, metabolic defects, and male infertility in vitro in a murine model.
Abe K, Fuchs H, Boersma A, Hans W, Yu P, Kalaydjiev S, Klaften M, Adler T, Calzada-Wack J, Mossbrugger I, Rathkolb B, Rozman J, Prehn C, Maraslioglu M, Kametani Y, Shimada S, Adamski J, Busch DH, Esposito I, Klingenspor M, Wolf E, Wurst W, Gailus-Durner V, Katan M, Marschall S, Soewarto D, Wagner S, de Angelis MH. Abe K, et al. Among authors: rathkolb b. Arthritis Rheum. 2011 May;63(5):1301-11. doi: 10.1002/art.30280. Arthritis Rheum. 2011. PMID: 21305534 Free article.
Loss of the actin remodeler Eps8 causes intestinal defects and improved metabolic status in mice.
Tocchetti A, Soppo CB, Zani F, Bianchi F, Gagliani MC, Pozzi B, Rozman J, Elvert R, Ehrhardt N, Rathkolb B, Moerth C, Horsch M, Fuchs H, Gailus-Durner V, Beckers J, Klingenspor M, Wolf E, Hrabé de Angelis M, Scanziani E, Tacchetti C, Scita G, Di Fiore PP, Offenhäuser N. Tocchetti A, et al. Among authors: rathkolb b. PLoS One. 2010 Mar 2;5(3):e9468. doi: 10.1371/journal.pone.0009468. PLoS One. 2010. PMID: 20209148 Free PMC article.
Identification of immunological relevant phenotypes in ENU mutagenized mice.
Flaswinkel H, Alessandrini F, Rathkolb B, Decker T, Kremmer E, Servatius A, Jakob T, Soewarto D, Marschall S, Fella C, Behrendt H, Ring J, Wolf E, Balling R, Hrabé de Angelis M, Pfeffer K. Flaswinkel H, et al. Among authors: rathkolb b. Mamm Genome. 2000 Jul;11(7):526-7. doi: 10.1007/s003350010100. Mamm Genome. 2000. PMID: 10886016
Novel mouse mutants with primary cellular immunodeficiencies generated by genome-wide mutagenesis.
Jakob T, Köllisch GV, Howaldt M, Bewersdorff M, Rathkolb B, Müller ML, Sandholzer N, Nitschke L, Schiemann M, Mempel M, Ollert M, Neubauer A, Soewarto DA, Kremmer E, Ring J, Behrendt H, Flaswinkel H. Jakob T, et al. Among authors: rathkolb b. J Allergy Clin Immunol. 2008 Jan;121(1):179-184.e7. doi: 10.1016/j.jaci.2007.07.018. Epub 2007 Sep 4. J Allergy Clin Immunol. 2008. PMID: 17767948
166 results