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Base editor scanning charts the DNMT3A activity landscape.
Lue NZ, Garcia EM, Ngan KC, Lee C, Doench JG, Liau BB. Lue NZ, et al. Among authors: lee c. Nat Chem Biol. 2023 Feb;19(2):176-186. doi: 10.1038/s41589-022-01167-4. Epub 2022 Oct 20. Nat Chem Biol. 2023. PMID: 36266353 Free PMC article.
KBTBD4 Cancer Hotspot Mutations Drive Neomorphic Degradation of HDAC1/2 Corepressor Complexes.
Xie X, Zhang O, Yeo MJR, Lee C, Harry SA, Paul L, Li Y, Payne NC, Nam E, Kwok HS, Jiang H, Mao H, Hadley JL, Lin H, Batts M, Gosavi PM, D'Angiolella V, Cole PA, Mazitschek R, Northcott PA, Zheng N, Liau BB. Xie X, et al. Among authors: lee c. bioRxiv [Preprint]. 2024 May 14:2024.05.14.593970. doi: 10.1101/2024.05.14.593970. bioRxiv. 2024. PMID: 38798357 Free PMC article. Preprint.
Asymmetric Engagement of Dimeric CRL3 KBTBD4 by the Molecular Glue UM171 Licenses Degradation of HDAC1/2 Complexes.
Yeo MJ, Zhang O, Xie X, Nam E, Payne NC, Gosavi PM, Kwok HS, Iram I, Lee C, Li J, Chen NJ, Jiang H, Wang ZA, Lee K, Mao H, Harry SA, Barakat IA, Takahashi M, Waterbury AL, Barone M, Mattevi A, Bar-Peled L, Cole PA, Mazitschek R, Liau BB, Zheng N. Yeo MJ, et al. Among authors: lee k, lee c. bioRxiv [Preprint]. 2024 May 14:2024.05.14.593897. doi: 10.1101/2024.05.14.593897. bioRxiv. 2024. PMID: 38798619 Free PMC article. Preprint.
An autoinhibitory switch of the LSD1 disordered region controls enhancer silencing.
Waterbury AL, Kwok HS, Lee C, Narducci DN, Freedy AM, Su C, Raval S, Reiter AH, Hawkins W, Lee K, Li J, Hoenig SM, Vinyard ME, Cole PA, Hansen AS, Carr SA, Papanastasiou M, Liau BB. Waterbury AL, et al. Among authors: lee k, lee c. Mol Cell. 2024 Jun 20;84(12):2238-2254.e11. doi: 10.1016/j.molcel.2024.05.017. Epub 2024 Jun 12. Mol Cell. 2024. PMID: 38870936
A functional genomics screen identifying blood cell development genes in Drosophila by undergraduates participating in a course-based research experience.
Evans CJ, Olson JM, Mondal BC, Kandimalla P, Abbasi A, Abdusamad MM, Acosta O, Ainsworth JA, Akram HM, Albert RB, Alegria-Leal E, Alexander KY, Ayala AC, Balashova NS, Barber RM, Bassi H, Bennion SP, Beyder M, Bhatt KV, Bhoot C, Bradshaw AW, Brannigan TG, Cao B, Cashell YY, Chai T, Chan AW, Chan C, Chang I, Chang J, Chang MT, Chang PW, Chang S, Chari N, Chassiakos AJ, Chen IE, Chen VK, Chen Z, Cheng MR, Chiang M, Chiu V, Choi S, Chung JH, Contreras L, Corona E, Cruz CJ, Cruz RL, Dang JM, Dasari SP, De La Fuente JRO, Del Rio OMA, Dennis ER, Dertsakyan PS, Dey I, Distler RS, Dong Z, Dorman LC, Douglass MA, Ehresman AB, Fu IH, Fua A, Full SM, Ghaffari-Rafi A, Ghani AA, Giap B, Gill S, Gill ZS, Gills NJ, Godavarthi S, Golnazarian T, Goyal R, Gray R, Grunfeld AM, Gu KM, Gutierrez NC, Ha AN, Hamid I, Hanson A, Hao C, He C, He M, Hedtke JP, Hernandez YK, Hlaing H, Hobby FA, Hoi K, Hope AC, Hosseinian SM, Hsu A, Hsueh J, Hu E, Hu SS, Huang S, Huang W, Huynh M, Javier C, Jeon NE, Ji S, Johal J, John A, Johnson L, Kadakia S, Kakade N, Kamel S, Kaur R, Khatra JS, Kho JA, Kim C, Kim EJ, Kim HJ, Kim HW, Kim JH, Kim SA, Kim WK, Kit B, La C, Lai J, Lam V, Le NK, Lee CJ, Lee D See abstract for full author list ➔ Evans CJ, et al. Among authors: lee dy, lee d, lee cj, lee g, lee v, lee sk, lee j, lee jy, lee tc, lee o, lee s, lee c. G3 (Bethesda). 2021 Jan 18;11(1):jkaa028. doi: 10.1093/g3journal/jkaa028. G3 (Bethesda). 2021. PMID: 33561251 Free PMC article.
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