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Page 1
Aberrant phase separation and nucleolar dysfunction in rare genetic diseases.
Mensah MA, Niskanen H, Magalhaes AP, Basu S, Kircher M, Sczakiel HL, Reiter AMV, Elsner J, Meinecke P, Biskup S, Chung BHY, Dombrowsky G, Eckmann-Scholz C, Hitz MP, Hoischen A, Holterhus PM, Hülsemann W, Kahrizi K, Kalscheuer VM, Kan A, Krumbiegel M, Kurth I, Leubner J, Longardt AC, Moritz JD, Najmabadi H, Skipalova K, Snijders Blok L, Tzschach A, Wiedersberg E, Zenker M, Garcia-Cabau C, Buschow R, Salvatella X, Kraushar ML, Mundlos S, Caliebe A, Spielmann M, Horn D, Hnisz D. Mensah MA, et al. Among authors: kraushar ml. Nature. 2023 Feb;614(7948):564-571. doi: 10.1038/s41586-022-05682-1. Epub 2023 Feb 8. Nature. 2023. PMID: 36755093 Free PMC article.
Molecular crowding and RNA synergize to promote phase separation, microtubule interaction, and seeding of Tau condensates.
Hochmair J, Exner C, Franck M, Dominguez-Baquero A, Diez L, Brognaro H, Kraushar ML, Mielke T, Radbruch H, Kaniyappan S, Falke S, Mandelkow E, Betzel C, Wegmann S. Hochmair J, et al. Among authors: kraushar ml. EMBO J. 2022 Jun 1;41(11):e108882. doi: 10.15252/embj.2021108882. Epub 2022 Mar 17. EMBO J. 2022. PMID: 35298090 Free PMC article.
A critical period of translational control during brain development at codon resolution.
Harnett D, Ambrozkiewicz MC, Zinnall U, Rusanova A, Borisova E, Drescher AN, Couce-Iglesias M, Villamil G, Dannenberg R, Imami K, Münster-Wandowski A, Fauler B, Mielke T, Selbach M, Landthaler M, Spahn CMT, Tarabykin V, Ohler U, Kraushar ML. Harnett D, et al. Among authors: kraushar ml. Nat Struct Mol Biol. 2022 Dec;29(12):1277-1290. doi: 10.1038/s41594-022-00882-9. Epub 2022 Dec 8. Nat Struct Mol Biol. 2022. PMID: 36482253 Free PMC article.
Protein translation rate determines neocortical neuron fate.
Borisova E, Newman AG, Couce Iglesias M, Dannenberg R, Schaub T, Qin B, Rusanova A, Brockmann M, Koch J, Daniels M, Turko P, Jahn O, Kaplan DR, Rosário M, Iwawaki T, Spahn CMT, Rosenmund C, Meierhofer D, Kraushar ML, Tarabykin V, Ambrozkiewicz MC. Borisova E, et al. Among authors: kraushar ml. Nat Commun. 2024 Jun 7;15(1):4879. doi: 10.1038/s41467-024-49198-w. Nat Commun. 2024. PMID: 38849354 Free PMC article.
Translational derepression of Elavl4 isoforms at their alternative 5' UTRs determines neuronal development.
Popovitchenko T, Park Y, Page NF, Luo X, Krsnik Z, Liu Y, Salamon I, Stephenson JD, Kraushar ML, Volk NL, Patel SM, Wijeratne HRS, Li D, Suthar KS, Wach A, Sun M, Arnold SJ, Akamatsu W, Okano H, Paillard L, Zhang H, Buyske S, Kostovic I, De Rubeis S, Hart RP, Rasin MR. Popovitchenko T, et al. Among authors: kraushar ml. Nat Commun. 2020 Apr 3;11(1):1674. doi: 10.1038/s41467-020-15412-8. Nat Commun. 2020. PMID: 32245946 Free PMC article.
Protein Synthesis in the Developing Neocortex at Near-Atomic Resolution Reveals Ebp1-Mediated Neuronal Proteostasis at the 60S Tunnel Exit.
Kraushar ML, Krupp F, Harnett D, Turko P, Ambrozkiewicz MC, Sprink T, Imami K, Günnigmann M, Zinnall U, Vieira-Vieira CH, Schaub T, Münster-Wandowski A, Bürger J, Borisova E, Yamamoto H, Rasin MR, Ohler U, Beule D, Mielke T, Tarabykin V, Landthaler M, Kramer G, Vida I, Selbach M, Spahn CMT. Kraushar ML, et al. Mol Cell. 2021 Jan 21;81(2):304-322.e16. doi: 10.1016/j.molcel.2020.11.037. Epub 2020 Dec 22. Mol Cell. 2021. PMID: 33357414 Free PMC article.
Ribosomal RNA 2'-O-methylation dynamics impact cell fate decisions.
Häfner SJ, Jansson MD, Altinel K, Andersen KL, Abay-Nørgaard Z, Ménard P, Fontenas M, Sørensen DM, Gay DM, Arendrup FS, Tehler D, Krogh N, Nielsen H, Kraushar ML, Kirkeby A, Lund AH. Häfner SJ, et al. Among authors: kraushar ml. Dev Cell. 2023 Sep 11;58(17):1593-1609.e9. doi: 10.1016/j.devcel.2023.06.007. Epub 2023 Jul 19. Dev Cell. 2023. PMID: 37473757 Free article.
Decoding a ribosome uncertainty.
Duss O, Nikolay R, Kraushar ML. Duss O, et al. Among authors: kraushar ml. Trends Genet. 2023 Sep;39(9):639-641. doi: 10.1016/j.tig.2023.06.001. Epub 2023 Jun 26. Trends Genet. 2023. PMID: 37380507
15 results