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The DataHarmonizer: a tool for faster data harmonization, validation, aggregation and analysis of pathogen genomics contextual information.
Gill IS, Griffiths EJ, Dooley D, Cameron R, Savić Kallesøe S, John NS, Sehar A, Gosal G, Alexander D, Chapel M, Croxen MA, Delisle B, Di Tullio R, Gaston D, Duggan A, Guthrie JL, Horsman M, Joshi E, Kearny L, Knox N, Lau L, LeBlanc JJ, Li V, Lyons P, MacKenzie K, McArthur AG, Panousis EM, Palmer J, Prystajecky N, Smith KN, Tanner J, Townend C, Tyler A, Van Domselaar G, Hsiao WWL. Gill IS, et al. Among authors: smith kn. Microb Genom. 2023 Jan;9(1):mgen000908. doi: 10.1099/mgen.0.000908. Microb Genom. 2023. PMID: 36748616 Free PMC article.
A dominant RAD51C pathogenic splicing variant predisposes to breast and ovarian cancer in the Newfoundland population due to founder effect.
Dawson LM, Smith KN, Werdyani S, Ndikumana R, Penney C, Wiede LL, Smith KL, Pater JA, MacMillan A, Green J, Drover S, Young TL, O'Rielly DD. Dawson LM, et al. Among authors: smith kl, smith kn. Mol Genet Genomic Med. 2020 Feb;8(2):e1070. doi: 10.1002/mgg3.1070. Epub 2019 Nov 28. Mol Genet Genomic Med. 2020. PMID: 31782267 Free PMC article.
Divergent clinical and immunologic outcomes based on STK11 co-mutation status in resectable KRAS-mutant lung cancers following neoadjuvant immune checkpoint blockade.
Rosner S, Connor S, Sanber K, Zahurak M, Zhang T, Gurumurthy I, Zeng Z, Presson B, Singh D, Rayes R, Sivapalan L, Pereira G, Ji Z, Thummalapalli R, Reuss JE, Broderick SR, Jones DR, Deutsch JS, Cottrell TR, Chaft J, Spicer J, Taube J, Anagnostou V, Brahmer JR, Pardoll DM, Ji H, Forde PM, Marrone KA, Smith KN. Rosner S, et al. Among authors: smith kn. Clin Cancer Res. 2024 Nov 15. doi: 10.1158/1078-0432.CCR-24-2983. Online ahead of print. Clin Cancer Res. 2024. PMID: 39545922
Precise identification and tracking of HMGCR-reactive CD4+ T cells in the target tissue of patients with anti-HMGCR immune-mediated necrotising myopathy.
Tiniakou E, Girgis A, Siafei T, Albayda J, Adler B, Paik JJ, Mecoli CA, Rebman A, Soloski MJ, Christopher-Stine L, Smith KN, Rosen A, Mammen AL, Darrah E. Tiniakou E, et al. Among authors: smith kn. Ann Rheum Dis. 2024 Oct 11:ard-2024-225732. doi: 10.1136/ard-2024-225732. Online ahead of print. Ann Rheum Dis. 2024. PMID: 39393845
Structural basis for VLDLR recognition by eastern equine encephalitis virus.
Yang P, Li W, Fan X, Pan J, Mann CJ, Varnum H, Clark LE, Clark SA, Coscia A, Basu H, Smith KN, Brusic V, Abraham J. Yang P, et al. Among authors: smith kn. Nat Commun. 2024 Aug 2;15(1):6548. doi: 10.1038/s41467-024-50887-9. Nat Commun. 2024. PMID: 39095394 Free PMC article.
135 results