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Compressed phenotypic screens for complex multicellular models and high-content assays.
Mead BE, Kummerlowe C, Liu N, Kattan WE, Cheng T, Cheah JH, Soule CK, Peters J, Lowder KE, Blainey PC, Hahn WC, Cleary B, Bryson B, Winter PS, Raghavan S, Shalek AK. Mead BE, et al. Among authors: bryson b. bioRxiv [Preprint]. 2023 Jan 23:2023.01.23.525189. doi: 10.1101/2023.01.23.525189. bioRxiv. 2023. PMID: 36747859 Free PMC article. Preprint.
Variability in tuberculosis granuloma T cell responses exists, but a balance of pro- and anti-inflammatory cytokines is associated with sterilization.
Gideon HP, Phuah J, Myers AJ, Bryson BD, Rodgers MA, Coleman MT, Maiello P, Rutledge T, Marino S, Fortune SM, Kirschner DE, Lin PL, Flynn JL. Gideon HP, et al. PLoS Pathog. 2015 Jan 22;11(1):e1004603. doi: 10.1371/journal.ppat.1004603. eCollection 2015 Jan. PLoS Pathog. 2015. PMID: 25611466 Free PMC article.
The bromodomain protein Brd4 insulates chromatin from DNA damage signalling.
Floyd SR, Pacold ME, Huang Q, Clarke SM, Lam FC, Cannell IG, Bryson BD, Rameseder J, Lee MJ, Blake EJ, Fydrych A, Ho R, Greenberger BA, Chen GC, Maffa A, Del Rosario AM, Root DE, Carpenter AE, Hahn WC, Sabatini DM, Chen CC, White FM, Bradner JE, Yaffe MB. Floyd SR, et al. Among authors: bryson bd. Nature. 2013 Jun 13;498(7453):246-50. doi: 10.1038/nature12147. Epub 2013 Jun 2. Nature. 2013. PMID: 23728299 Free PMC article.
The cellular architecture of the antimicrobial response network in human leprosy granulomas.
Ma F, Hughes TK, Teles RMB, Andrade PR, de Andrade Silva BJ, Plazyo O, Tsoi LC, Do T, Wadsworth MH 2nd, Oulee A, Ochoa MT, Sarno EN, Iruela-Arispe ML, Klechevsky E, Bryson B, Shalek AK, Bloom BR, Gudjonsson JE, Pellegrini M, Modlin RL. Ma F, et al. Among authors: bryson b. Nat Immunol. 2021 Jul;22(7):839-850. doi: 10.1038/s41590-021-00956-8. Epub 2021 Jun 24. Nat Immunol. 2021. PMID: 34168371 Free PMC article.
Multimodal profiling of lung granulomas in macaques reveals cellular correlates of tuberculosis control.
Gideon HP, Hughes TK, Tzouanas CN, Wadsworth MH 2nd, Tu AA, Gierahn TM, Peters JM, Hopkins FF, Wei JR, Kummerlowe C, Grant NL, Nargan K, Phuah JY, Borish HJ, Maiello P, White AG, Winchell CG, Nyquist SK, Ganchua SKC, Myers A, Patel KV, Ameel CL, Cochran CT, Ibrahim S, Tomko JA, Frye LJ, Rosenberg JM, Shih A, Chao M, Klein E, Scanga CA, Ordovas-Montanes J, Berger B, Mattila JT, Madansein R, Love JC, Lin PL, Leslie A, Behar SM, Bryson B, Flynn JL, Fortune SM, Shalek AK. Gideon HP, et al. Among authors: bryson b. Immunity. 2022 May 10;55(5):827-846.e10. doi: 10.1016/j.immuni.2022.04.004. Epub 2022 Apr 27. Immunity. 2022. PMID: 35483355 Free PMC article.
Tregs constrain CD8+ T cell priming required for curative intratumorally anchored anti-4-1BB immunotherapy.
Palmeri JR, Lax BM, Peters JM, Duhamel L, Stinson JA, Santollani L, Lutz EA, Pinney W 3rd, Bryson BD, Wittrup KD. Palmeri JR, et al. bioRxiv [Preprint]. 2023 Feb 1:2023.01.30.526116. doi: 10.1101/2023.01.30.526116. bioRxiv. 2023. Update in: Nat Commun. 2024 Mar 1;15(1):1900. doi: 10.1038/s41467-024-45625-0 PMID: 36778460 Free PMC article. Updated. Preprint.
Protective intravenous BCG vaccination induces enhanced immune signaling in the airways.
Peters JM, Irvine EB, Rosenberg JM, Wadsworth MH, Hughes TK, Sutton M, Nyquist SK, Bromley JD, Mondal R, Roederer M, Seder RA, Darrah PA, Alter G, Flynn JL, Shalek AK, Fortune SM, Bryson BD. Peters JM, et al. Among authors: bryson bd. bioRxiv [Preprint]. 2023 Jul 18:2023.07.16.549208. doi: 10.1101/2023.07.16.549208. bioRxiv. 2023. PMID: 37502895 Free PMC article. Preprint.
94 results