Brefeldin A inhibits colorectal cancer growth by triggering Bip/Akt-regulated autophagy.
Zhou L, Gao W, Wang K, Huang Z, Zhang L, Zhang Z, Zhou J, Nice EC, Huang C.
Zhou L, et al. Among authors: huang c, huang z.
FASEB J. 2019 Apr;33(4):5520-5534. doi: 10.1096/fj.201801983R. Epub 2019 Jan 22.
FASEB J. 2019.
PMID: 30668917
Collectively, our study provides an important molecular basis for BFA-induced autophagy and suggests that the antibiotic BFA could be repositioned as a potential anticancer drug for CRC treatment.-Zhou, L., Gao, W., Wang, K., Huang, Z., Zhang, L., Zhang, Z., …
Collectively, our study provides an important molecular basis for BFA-induced autophagy and suggests that the antibiotic BFA could be reposi …