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A recurrent missense variant in ITPR3 causes demyelinating Charcot-Marie-Tooth with variable severity.
Beijer D, Dohrn MF, Rebelo A, Danzi MC, Grosz BR, Ellis M, Kumar KR, Vucic S, Vais H, Weissenrieder JS, Lunko O, Paudel U, Simpson LC, Camarena V, Raposo J, Saporta M, Arcia Y, Xu I, Feely S, Record CJ, Blake J, Reilly MM, Scherer SS, Kennerson M, Lee YC, Foskett JK, Shy ME, Zuchner S. Beijer D, et al. Among authors: foskett jk. Brain. 2025 Jan 7;148(1):227-237. doi: 10.1093/brain/awae206. Brain. 2025. PMID: 38938188
The mitochondrial Ca 2+ channel MCU is critical for tumor growth by supporting cell cycle progression and proliferation.
García EF, Paudel U, Noji MC, Bowman CE, Pitarresi JR, Rustgi AK, Wellen KE, Arany Z, Weissenrieder JS, Foskett JK. García EF, et al. Among authors: foskett jk. bioRxiv [Preprint]. 2023 Apr 28:2023.04.26.538295. doi: 10.1101/2023.04.26.538295. bioRxiv. 2023. Update in: Front Cell Dev Biol. 2023 Jun 08;11:1082213. doi: 10.3389/fcell.2023.1082213 PMID: 37163088 Free PMC article. Updated. Preprint.
Mitochondrial Ca2+ controls pancreatic cancer growth and metastasis by regulating epithelial cell plasticity.
Weissenrieder JS, Peura J, Paudel U, Bhalerao N, Weinmann N, Johnson C, Wengyn M, Drager R, Furth EE, Simin K, Ruscetti M, Stanger BZ, Rustgi AK, Pitarresi JR, Foskett JK. Weissenrieder JS, et al. Among authors: foskett jk. bioRxiv [Preprint]. 2024 Aug 9:2024.08.08.607195. doi: 10.1101/2024.08.08.607195. bioRxiv. 2024. PMID: 39149344 Free PMC article. Preprint.
LNS8801 inhibits Acute Myeloid Leukemia by Inducing the Production of Reactive Oxygen Species and Activating the Endoplasmic Reticulum Stress Pathway.
Lee I, Doepner M, Weissenrieder J, Majer AD, Mercado S, Estell A, Natale CA, Sung PJ, Foskett JK, Carroll MP, Ridky TW. Lee I, et al. Among authors: foskett jk. Cancer Res Commun. 2023 Aug 18;3(8):1594-1606. doi: 10.1158/2767-9764.CRC-22-0478. eCollection 2023 Aug. Cancer Res Commun. 2023. PMID: 37599786 Free PMC article.
ZIP9 Is a Druggable Determinant of Sex Differences in Melanoma.
Aguirre-Portolés C, Payne R, Trautz A, Foskett JK, Natale CA, Seykora JT, Ridky TW. Aguirre-Portolés C, et al. Among authors: foskett jk. Cancer Res. 2021 Dec 1;81(23):5991-6003. doi: 10.1158/0008-5472.CAN-21-0982. Epub 2021 Oct 27. Cancer Res. 2021. PMID: 34706862 Free PMC article.
Calcium signaling induces a partial EMT.
Norgard RJ, Pitarresi JR, Maddipati R, Aiello-Couzo NM, Balli D, Li J, Yamazoe T, Wengyn MD, Millstein ID, Folkert IW, Rosario-Berrios DN, Kim IK, Bassett JB, Payne R, Berry CT, Feng X, Sun K, Cioffi M, Chakraborty P, Jolly MK, Gutkind JS, Lyden D, Freedman BD, Foskett JK, Rustgi AK, Stanger BZ. Norgard RJ, et al. Among authors: foskett jk. EMBO Rep. 2021 Sep 6;22(9):e51872. doi: 10.15252/embr.202051872. Epub 2021 Jul 29. EMBO Rep. 2021. PMID: 34324787 Free PMC article.
175 results