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NRF2 controls iron homeostasis and ferroptosis through HERC2 and VAMP8.
Anandhan A, Dodson M, Shakya A, Chen J, Liu P, Wei Y, Tan H, Wang Q, Jiang Z, Yang K, Garcia JG, Chambers SK, Chapman E, Ooi A, Yang-Hartwich Y, Stockwell BR, Zhang DD. Anandhan A, et al. Among authors: ooi a. Sci Adv. 2023 Feb 3;9(5):eade9585. doi: 10.1126/sciadv.ade9585. Epub 2023 Feb 1. Sci Adv. 2023. PMID: 36724221 Free PMC article.
Oncogenic KRAS confers chemoresistance by upregulating NRF2.
Tao S, Wang S, Moghaddam SJ, Ooi A, Chapman E, Wong PK, Zhang DD. Tao S, et al. Among authors: ooi a. Cancer Res. 2014 Dec 15;74(24):7430-41. doi: 10.1158/0008-5472.CAN-14-1439. Epub 2014 Oct 22. Cancer Res. 2014. PMID: 25339352 Free PMC article.
The Roles of NRF2 in Modulating Cellular Iron Homeostasis.
Kerins MJ, Ooi A. Kerins MJ, et al. Among authors: ooi a. Antioxid Redox Signal. 2018 Dec 10;29(17):1756-1773. doi: 10.1089/ars.2017.7176. Epub 2017 Sep 21. Antioxid Redox Signal. 2018. PMID: 28793787 Free PMC article. Review.
329 results