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Trans-ancestry genome-wide study of depression identifies 697 associations implicating cell types and pharmacotherapies.
Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium. Electronic address: andrew.mcintosh@ed.ac.uk; Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium. Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium. Electronic address: andrew.mcintosh@ed.ac.uk, et al. Cell. 2025 Jan 14:S0092-8674(24)01415-6. doi: 10.1016/j.cell.2024.12.002. Online ahead of print. Cell. 2025. PMID: 39814019 Free article.
Genome-wide meta-analysis of ascertainment and symptom structures of major depression in case-enriched and community cohorts.
Adams MJ, Thorp JG, Jermy BS, Kwong ASF, Kõiv K, Grotzinger AD, Nivard MG, Marshall S, Milaneschi Y, Baune BT, Müller-Myhsok B, Penninx BWJH, Boomsma DI, Levinson DF, Breen G, Pistis G, Grabe HJ, Tiemeier H, Berger K, Rietschel M, Magnusson PK, Uher R, Hamilton SP, Lucae S, Lehto K, Li QS, Byrne EM, Hickie IB, Martin NG, Medland SE, Wray NR, Tucker-Drob EM; Estonian Biobank Research Team; Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium; Lewis CM, McIntosh AM, Derks EM. Adams MJ, et al. Psychol Med. 2024 Sep;54(12):3459-3468. doi: 10.1017/S0033291724001880. Epub 2024 Sep 26. Psychol Med. 2024. PMID: 39324397 Free PMC article.
Genome-wide association study of major anxiety disorders in 122,341 European-ancestry cases identifies 58 loci and highlights GABAergic signaling.
Strom NI, Verhulst B, Bacanu SA, Cheesman R, Purves KL, Gedik H, Mitchell BL, Kwong AS, Faucon AB, Singh K, Medland S, Colodro-Conde L, Krebs K, Hoffmann P, Herms S, Gehlen J, Ripke S, Awasthi S, Palviainen T, Tasanko EM, Peterson RE, Adkins DE, Shabalin AA, Adams MJ, Iveson MH, Campbell A, Thomas LF, Winsvold BS, Drange OK, Børte S, Ter Kuile AR, Nguyen TH, Meier SM, Corfield EC, Hannigan L, Levey DF, Czamara D, Weber H, Choi KW, Pistis G, Couvy-Duchesne B, Van der Auwera S, Teumer A, Karlsson R, Garcia-Argibay M, Lee D, Wang R, Bjerkeset O, Stordal E, Bäckmann J, Salum GA, Zai CC, Kennedy JL, Zai G, Tiwari AK, Heilmann-Heimbach S, Schmidt B, Kaprio J, Kennedy MM, Boden J, Havdahl A, Middeldorp CM, Lopes FL, Akula N, McMahon FJ, Binder EB, Fehm L, Ströhle A, Castelao E, Tiemeier H, Stein DJ, Whiteman D, Olsen C, Fuller Z, Wang X, Wray NR, Byrne EM, Lewis G, Timpson NJ, Davis LK, Hickie IB, Gillespie NA, Milani L, Schumacher J, Woldbye DP, Forstner AJ, Nöthen MM, Hovatta I, Horwood J, Copeland WE, Maes HH, McIntosh AM, Andreassen OA, Zwart JA, Mors O, Børglum AD, Mortensen PB, Ask H, Reichborn-Kjennerud T, Najman JM, Stein MB, Gelernter J, Milaneschi Y, Penninx BW, Boomsma … See abstract for full author list ➔ Strom NI, et al. Among authors: adams mj. medRxiv [Preprint]. 2024 Jul 5:2024.07.03.24309466. doi: 10.1101/2024.07.03.24309466. medRxiv. 2024. PMID: 39006447 Free PMC article. Preprint.
A comprehensive hierarchical comparison of structural connectomes in Major Depressive Disorder cases v. controls in two large population samples.
Thng G, Shen X, Stolicyn A, Adams MJ, Yeung HW, Batziou V, Conole ELS, Buchanan CR, Lawrie SM, Bastin ME, McIntosh AM, Deary IJ, Tucker-Drob EM, Cox SR, Smith KM, Romaniuk L, Whalley HC. Thng G, et al. Among authors: adams mj. Psychol Med. 2024 Jul;54(10):2515-2526. doi: 10.1017/S0033291724000643. Epub 2024 Mar 18. Psychol Med. 2024. PMID: 38497116 Free article.
Distinguishing different psychiatric disorders using DDx-PRS.
Peyrot WJ, Panagiotaropoulou G, Olde Loohuis LM, Adams MJ, Awasthi S, Ge T, McIntosh AM, Mitchell BL, Mullins N, O'Connell KS, Penninx BWJH, Posthuma D, Ripke S, Ruderfer DM, Uffelmann E, Vilhjalmsson BJ, Zhu Z; Schizophrenia Working Group of the Psychiatric Genomics Consortium; Bipolar Disorder Working Group of the Psychiatric Genomics Consortium; Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium; Smoller JW, Price AL. Peyrot WJ, et al. Among authors: adams mj. medRxiv [Preprint]. 2024 Feb 4:2024.02.02.24302228. doi: 10.1101/2024.02.02.24302228. medRxiv. 2024. PMID: 38352307 Free PMC article. Preprint.
Chytrid infections exhibit historical spread and contemporary seasonality in a declining stream-breeding frog.
Belasen AM, Peek RA, Adams AJ, Russell ID, De León ME, Adams MJ, Bettaso J, Breedveld KGH, Catenazzi A, Dillingham CP, Grear DA, Halstead BJ, Johnson PG, Kleeman PM, Koo MS, Koppl CW, Lauder JD, Padgett-Flohr G, Piovia-Scott J, Pope KL, Vredenburg V, Westphal M, Wiseman K, Kupferberg SJ. Belasen AM, et al. Among authors: adams mj. R Soc Open Sci. 2024 Jan 31;11(1):231270. doi: 10.1098/rsos.231270. eCollection 2024 Jan. R Soc Open Sci. 2024. PMID: 38298390 Free PMC article.
522 results