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Exogenous butyrate inhibits butyrogenic metabolism and alters expression of virulence genes in Clostridioides difficile.
Pensinger DA, Dobrila HA, Stevenson DM, Davis NM, Amador-Noguez D, Hryckowian AJ. Pensinger DA, et al. Among authors: dobrila ha. bioRxiv [Preprint]. 2023 Jul 6:2023.07.06.548018. doi: 10.1101/2023.07.06.548018. bioRxiv. 2023. Update in: mBio. 2024 Mar 13;15(3):e0253523. doi: 10.1128/mbio.02535-23 PMID: 37461482 Free PMC article. Updated. Preprint.
Butyrate Differentiates Permissiveness to Clostridioides difficile Infection and Influences Growth of Diverse C. difficile Isolates.
Pensinger DA, Fisher AT, Dobrila HA, Van Treuren W, Gardner JO, Higginbottom SK, Carter MM, Schumann B, Bertozzi CR, Anikst V, Martin C, Robilotti EV, Chow JM, Buck RH, Tompkins LS, Sonnenburg JL, Hryckowian AJ. Pensinger DA, et al. Among authors: dobrila ha. Infect Immun. 2023 Feb 16;91(2):e0057022. doi: 10.1128/iai.00570-22. Epub 2023 Jan 24. Infect Immun. 2023. PMID: 36692308 Free PMC article.