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Dysregulated complement activation during acute myocardial infarction leads to endothelial glycocalyx degradation and endothelial dysfunction via the C5a:C5a-Receptor1 axis.
Vahldieck C, Löning S, Hamacher C, Fels B, Rudzewski B, Nickel L, Weil J, Nording H, Baron L, Kleingarn M, Karsten CM, Kusche-Vihrog K. Vahldieck C, et al. Among authors: karsten cm. Front Immunol. 2024 Jul 11;15:1426526. doi: 10.3389/fimmu.2024.1426526. eCollection 2024. Front Immunol. 2024. PMID: 39055717 Free PMC article.
Endothelial Glycocalyx and Cardiomyocyte Damage Is Prevented by Recombinant Syndecan-1 in Acute Myocardial Infarction.
Vahldieck C, Cianflone E, Fels B, Löning S, Depelmann P, Sabatino J, Salerno N, Karsten CM, Torella D, Weil J, Sun D, Goligorsky MS, Kusche-Vihrog K. Vahldieck C, et al. Among authors: karsten cm. Am J Pathol. 2023 Apr;193(4):474-492. doi: 10.1016/j.ajpath.2022.12.009. Epub 2023 Jan 18. Am J Pathol. 2023. PMID: 36669683 Free PMC article.
Differential expression of C5aR1 and C5aR2 in innate and adaptive immune cells located in early skin lesions of bullous pemphigoid patients.
Emtenani S, Holtsche MM, Stahlkopf R, Seiler DL, Burn T, Liu H, Parker M, Yilmaz K, Dikmen HO, Lang MH, Sadik CD, Karsten CM, van Beek N, Ludwig RJ, Köhl J, Schmidt E. Emtenani S, et al. Among authors: karsten cm. Front Immunol. 2022 Nov 18;13:942493. doi: 10.3389/fimmu.2022.942493. eCollection 2022. Front Immunol. 2022. PMID: 36466856 Free PMC article.
Autoimmune pre-disease.
Bieber K, Hundt JE, Yu X, Ehlers M, Petersen F, Karsten CM, Köhl J, Kridin K, Kalies K, Kasprick A, Goletz S, Humrich JY, Manz RA, Künstner A, Hammers CM, Akbarzadeh R, Busch H, Sadik CD, Lange T, Grasshoff H, Hackel AM, Erdmann J, König I, Raasch W, Becker M, Kerstein-Stähle A, Lamprecht P, Riemekasten G, Schmidt E, Ludwig RJ. Bieber K, et al. Among authors: karsten cm. Autoimmun Rev. 2023 Feb;22(2):103236. doi: 10.1016/j.autrev.2022.103236. Epub 2022 Nov 24. Autoimmun Rev. 2023. PMID: 36436750 Review.
Low Concentrations of C5a Complement Receptor Antibodies Are Linked to Disease Activity and Relapse in Antineutrophil Cytoplasmic Autoantibody-Associated Vasculitis.
Klapa S, Müller A, Koch A, Kerstein-Stähle A, Kähler W, Heidecke H, Schinke S, Huber-Lang M, Nitschke M, Pitann S, Augustin S, Karsten CM, Riemekasten G, Lamprecht P. Klapa S, et al. Among authors: karsten cm. Arthritis Rheumatol. 2023 May;75(5):760-767. doi: 10.1002/art.42410. Epub 2023 Feb 22. Arthritis Rheumatol. 2023. PMID: 36409567
The relevance of complement in pemphigoid diseases: A critical appraisal.
Papara C, Karsten CM, Ujiie H, Schmidt E, Schmidt-Jiménez LF, Baican A, Freire PC, Izumi K, Bieber K, Peipp M, Verschoor A, Ludwig RJ, Köhl J, Zillikens D, Hammers CM. Papara C, et al. Among authors: karsten cm. Front Immunol. 2022 Aug 16;13:973702. doi: 10.3389/fimmu.2022.973702. eCollection 2022. Front Immunol. 2022. PMID: 36059476 Free PMC article. Review.
46 results