Wang G - Search Results

1

Ras superfamily GTPase activating proteins in cancer: Potential therapeutic targets?

Xiao H, Wang G, Zhao M, Shuai W, Ouyang L, Sun Q. Xiao H, et al. Among authors: wang g. Eur J Med Chem. 2023 Feb 15;248:115104. doi: 10.1016/j.ejmech.2023.115104. Epub 2023 Jan 10. Eur J Med Chem. 2023. PMID: 36641861 Review.

2

Discovery, Synthesis, and Evaluation of Highly Selective Vascular Endothelial Growth Factor Receptor 3 (VEGFR3) Inhibitor for the Potential Treatment of Metastatic Triple-Negative Breast Cancer.

Li Y, Yang G, Zhang J, Tang P, Yang C, Wang G, Chen J, Liu J, Zhang L, Ouyang L. Li Y, et al. Among authors: wang g. J Med Chem. 2021 Aug 26;64(16):12022-12048. doi: 10.1021/acs.jmedchem.1c00678. Epub 2021 Aug 5. J Med Chem. 2021. PMID: 34351741

3

Structure-Guided Design of a Small-Molecule Activator of Sirtuin-3 that Modulates Autophagy in Triple Negative Breast Cancer.

Zhang J, Zou L, Shi D, Liu J, Zhang J, Zhao R, Wang G, Zhang L, Ouyang L, Liu B. Zhang J, et al. Among authors: wang g. J Med Chem. 2021 Oct 14;64(19):14192-14216. doi: 10.1021/acs.jmedchem.0c02268. Epub 2021 Oct 3. J Med Chem. 2021. PMID: 34605238

4

Small Molecules Targeting Activated Cdc42-Associated Kinase 1 (ACK1/TNK2) for the Treatment of Cancers.

Wang A, Pei J, Shuai W, Lin C, Feng L, Wang Y, Lin F, Ouyang L, Wang G. Wang A, et al. Among authors: wang g, wang y. J Med Chem. 2021 Nov 25;64(22):16328-16348. doi: 10.1021/acs.jmedchem.1c01030. Epub 2021 Nov 4. J Med Chem. 2021. PMID: 34735773 Review.

5

Developing potent LC3-targeting AUTAC tools for protein degradation with selective autophagy.

Pei J, Pan X, Wang A, Shuai W, Bu F, Tang P, Zhang S, Zhang Y, Wang G, Ouyang L. Pei J, et al. Among authors: wang g, wang a. Chem Commun (Camb). 2021 Dec 7;57(97):13194-13197. doi: 10.1039/d1cc04661f. Chem Commun (Camb). 2021. PMID: 34816823

6

Discovery of Novel Dual-Target Inhibitor of Bromodomain-Containing Protein 4/Casein Kinase 2 Inducing Apoptosis and Autophagy-Associated Cell Death for Triple-Negative Breast Cancer Therapy.

Zhang J, Tang P, Zou L, Zhang J, Chen J, Yang C, He G, Liu B, Liu J, Chiang CM, Wang G, Ye T, Ouyang L. Zhang J, et al. Among authors: wang g. J Med Chem. 2021 Dec 23;64(24):18025-18053. doi: 10.1021/acs.jmedchem.1c01382. Epub 2021 Dec 15. J Med Chem. 2021. PMID: 34908415 Free PMC article.

7

Unraveling the Design and Discovery of c-Jun N-Terminal Kinase Inhibitors and Their Therapeutic Potential in Human Diseases.

Zhu Y, Shuai W, Zhao M, Pan X, Pei J, Wu Y, Bu F, Wang A, Ouyang L, Wang G. Zhu Y, et al. Among authors: wang g, wang a. J Med Chem. 2022 Mar 10;65(5):3758-3775. doi: 10.1021/acs.jmedchem.1c01947. Epub 2022 Feb 24. J Med Chem. 2022. PMID: 35200035

8

Design, synthesis and biological evaluation of novel diarylacylhydrazones derivatives for the efficient treatment of idiopathic pulmonary fibrosis.

Su X, Tan Z, Wang G, Liu Z, Gan C, Yue L, Liu H, Xie Y, Yao Y, Ye T. Su X, et al. Among authors: wang g. Eur J Med Chem. 2023 Jan 5;245(Pt 2):114918. doi: 10.1016/j.ejmech.2022.114918. Epub 2022 Nov 11. Eur J Med Chem. 2023. PMID: 36401884

9

Discovery of Novel Indazole Chemotypes as Isoform-Selective JNK3 Inhibitors for the Treatment of Parkinson's Disease.

Shuai W, Bu F, Zhu Y, Wu Y, Xiao H, Pan X, Zhang J, Sun Q, Wang G, Ouyang L. Shuai W, et al. Among authors: wang g. J Med Chem. 2023 Jan 26;66(2):1273-1300. doi: 10.1021/acs.jmedchem.2c01410. Epub 2023 Jan 17. J Med Chem. 2023. PMID: 36649216

10

Rational design and crystallographic analysis of novel isoform-selective TRKA inhibitors for cancer therapy.

Wang G, Wu Y, Wu C, Shuai W, Jiang T, Wang A, Bu F, Sun Q, Ouyang L. Wang G, et al. Among authors: wang a. Acta Pharm Sin B. 2023 Jan;13(1):440-443. doi: 10.1016/j.apsb.2022.10.012. Epub 2022 Oct 19. Acta Pharm Sin B. 2023. PMID: 36815052 Free PMC article. No abstract available.

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