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Chimeric hemagglutinin split vaccines elicit broadly cross-reactive antibodies and protection against group 2 influenza viruses in mice.
Puente-Massaguer E, Vasilev K, Beyer A, Loganathan M, Francis B, Scherm MJ, Arunkumar GA, González-Domínguez I, Zhu X, Wilson IA, Coughlan L, Sun W, Palese P, Krammer F. Puente-Massaguer E, et al. Among authors: loganathan m. Sci Adv. 2023 Sep 15;9(37):eadi4753. doi: 10.1126/sciadv.adi4753. Epub 2023 Sep 13. Sci Adv. 2023. PMID: 37703367 Free PMC article.
The immunodominance of antigenic site Sb on the H1 influenza virus hemagglutinin increases with high immunoglobulin titers of the cohorts and with young age, but not sex.
Martínez JL, Lemus N, Lai TY, Mishra M, González-Domínguez I, Puente-Massaguer E, Loganathan M, Francis B, Samanovic MI, Krammer F, Mulligan MJ, Simon V, Palese P, Sun W. Martínez JL, et al. Among authors: loganathan m. Vaccine. 2024 May 22;42(14):3365-3373. doi: 10.1016/j.vaccine.2024.04.037. Epub 2024 Apr 15. Vaccine. 2024. PMID: 38627145 Free article.
Bat-borne H9N2 influenza virus evades MxA restriction and exhibits efficient replication and transmission in ferrets.
Halwe NJ, Hamberger L, Sehl-Ewert J, Mache C, Schön J, Ulrich L, Calvelage S, Tönnies M, Fuchs J, Bandawane P, Loganathan M, Abbad A, Carreño JM, Bermúdez-González MC, Simon V, Kandeil A, El-Shesheny R, Ali MA, Kayali G, Budt M, Hippenstiel S, Hocke AC, Krammer F, Wolff T, Schwemmle M, Ciminski K, Hoffmann D, Beer M. Halwe NJ, et al. Among authors: loganathan m. Nat Commun. 2024 Apr 25;15(1):3450. doi: 10.1038/s41467-024-47455-6. Nat Commun. 2024. PMID: 38664395 Free PMC article.
A recombinant N2 neuraminidase-based CpG 1018® adjuvanted vaccine provides protection against challenge with heterologous influenza viruses in mice and hamsters.
Hoxie I, Vasilev K, Clark JJ, Bushfield K, Francis B, Loganathan M, Campbell JD, Yu D, Guan L, Gu C, Fan S, Tompkins SM, Neumann G, Kawaoka Y, Krammer F. Hoxie I, et al. Among authors: loganathan m. Vaccine. 2024 Oct 24;42(24):126269. doi: 10.1016/j.vaccine.2024.126269. Epub 2024 Sep 5. Vaccine. 2024. PMID: 39241354 Free article.
Sequential immunization with chimeric hemagglutinin ΔNS1 attenuated influenza vaccines induces broad humoral and cellular immunity.
Rathnasinghe R, Chang LA, Pearl R, Jangra S, Aspelund A, Hoag A, Yildiz S, Mena I, Sun W, Loganathan M, Crossland NA, Gertje HP, Tseng AE, Aslam S, Albrecht RA, Palese P, Krammer F, Schotsaert M, Muster T, García-Sastre A. Rathnasinghe R, et al. Among authors: loganathan m. NPJ Vaccines. 2024 Sep 16;9(1):169. doi: 10.1038/s41541-024-00952-7. NPJ Vaccines. 2024. PMID: 39300090 Free PMC article.
52 results