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Page 1
Elevated transferrin receptor impairs T cell metabolism and function in systemic lupus erythematosus.
Voss K, Sewell AE, Krystofiak ES, Gibson-Corley KN, Young AC, Basham JH, Sugiura A, Arner EN, Beavers WN, Kunkle DE, Dickson ME, Needle GA, Skaar EP, Rathmell WK, Ormseth MJ, Major AS, Rathmell JC. Voss K, et al. Among authors: rathmell jc, rathmell wk. Sci Immunol. 2023 Jan 13;8(79):eabq0178. doi: 10.1126/sciimmunol.abq0178. Epub 2023 Jan 13. Sci Immunol. 2023. PMID: 36638190 Free PMC article.
HIF1α and HIF2α exert distinct nutrient preferences in renal cells.
Arreola A, Cowey CL, Coloff JL, Rathmell JC, Rathmell WK. Arreola A, et al. Among authors: rathmell jc, rathmell wk. PLoS One. 2014 May 30;9(5):e98705. doi: 10.1371/journal.pone.0098705. eCollection 2014. PLoS One. 2014. PMID: 24879016 Free PMC article.
AMPK Is Essential to Balance Glycolysis and Mitochondrial Metabolism to Control T-ALL Cell Stress and Survival.
Kishton RJ, Barnes CE, Nichols AG, Cohen S, Gerriets VA, Siska PJ, Macintyre AN, Goraksha-Hicks P, de Cubas AA, Liu T, Warmoes MO, Abel ED, Yeoh AE, Gershon TR, Rathmell WK, Richards KL, Locasale JW, Rathmell JC. Kishton RJ, et al. Among authors: rathmell jc, rathmell wk. Cell Metab. 2016 Apr 12;23(4):649-62. doi: 10.1016/j.cmet.2016.03.008. Cell Metab. 2016. PMID: 27076078 Free PMC article.
Deep exploration of the immune infiltrate and outcome prediction in testicular cancer by quantitative multiplexed immunohistochemistry and gene expression profiling.
Siska PJ, Johnpulle RAN, Zhou A, Bordeaux J, Kim JY, Dabbas B, Dakappagari N, Rathmell JC, Rathmell WK, Morgans AK, Balko JM, Johnson DB. Siska PJ, et al. Among authors: rathmell jc, rathmell wk. Oncoimmunology. 2017 Mar 20;6(4):e1305535. doi: 10.1080/2162402X.2017.1305535. eCollection 2017. Oncoimmunology. 2017. PMID: 28507813 Free PMC article.
Mitochondrial dysregulation and glycolytic insufficiency functionally impair CD8 T cells infiltrating human renal cell carcinoma.
Siska PJ, Beckermann KE, Mason FM, Andrejeva G, Greenplate AR, Sendor AB, Chiang YJ, Corona AL, Gemta LF, Vincent BG, Wang RC, Kim B, Hong J, Chen CL, Bullock TN, Irish JM, Rathmell WK, Rathmell JC. Siska PJ, et al. Among authors: rathmell jc, rathmell wk. JCI Insight. 2017 Jun 15;2(12):e93411. doi: 10.1172/jci.insight.93411. eCollection 2017 Jun 15. JCI Insight. 2017. PMID: 28614802 Free PMC article.
Distinct Regulation of Th17 and Th1 Cell Differentiation by Glutaminase-Dependent Metabolism.
Johnson MO, Wolf MM, Madden MZ, Andrejeva G, Sugiura A, Contreras DC, Maseda D, Liberti MV, Paz K, Kishton RJ, Johnson ME, de Cubas AA, Wu P, Li G, Zhang Y, Newcomb DC, Wells AD, Restifo NP, Rathmell WK, Locasale JW, Davila ML, Blazar BR, Rathmell JC. Johnson MO, et al. Among authors: rathmell jc, rathmell wk. Cell. 2018 Dec 13;175(7):1780-1795.e19. doi: 10.1016/j.cell.2018.10.001. Epub 2018 Nov 1. Cell. 2018. PMID: 30392958 Free PMC article.
Macrophages Promote Aortic Valve Cell Calcification and Alter STAT3 Splicing.
Raddatz MA, Huffstater T, Bersi MR, Reinfeld BI, Madden MZ, Booton SE, Rathmell WK, Rathmell JC, Lindman BR, Madhur MS, Merryman WD. Raddatz MA, et al. Among authors: rathmell jc, rathmell wk. Arterioscler Thromb Vasc Biol. 2020 Jun;40(6):e153-e165. doi: 10.1161/ATVBAHA.120.314360. Epub 2020 Apr 16. Arterioscler Thromb Vasc Biol. 2020. PMID: 32295422 Free PMC article.
CD28 costimulation drives tumor-infiltrating T cell glycolysis to promote inflammation.
Beckermann KE, Hongo R, Ye X, Young K, Carbonell K, Healey DCC, Siska PJ, Barone S, Roe CE, Smith CC, Vincent BG, Mason FM, Irish JM, Rathmell WK, Rathmell JC. Beckermann KE, et al. Among authors: rathmell jc, rathmell wk. JCI Insight. 2020 Aug 20;5(16):e138729. doi: 10.1172/jci.insight.138729. JCI Insight. 2020. PMID: 32814710 Free PMC article.
311 results