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A mutant ASXL1-BAP1-EHMT complex contributes to heterochromatin dysfunction in clonal hematopoiesis and chronic monomyelocytic leukemia.
Dong Z, Sepulveda H, Arteaga-Vazquez LJ, Blouin C, Fernandez J, Binder M, Chou WC, Tien HF, Patnaik MM, Faulkner GJ, Myers SA, Rao A. Dong Z, et al. Among authors: sepulveda h. Proc Natl Acad Sci U S A. 2025 Jan 7;122(1):e2413302121. doi: 10.1073/pnas.2413302121. Epub 2025 Jan 3. Proc Natl Acad Sci U S A. 2025. PMID: 39752521
OGT prevents DNA demethylation and suppresses the expression of transposable elements in heterochromatin by restraining TET activity genome-wide.
Sepulveda H, Li X, Yue X, Carlos Angel J, Arteaga-Vazquez LJ, Brown C, Brunelli M, Jansz N, Puddu F, Scotcher J, Creed P, Kennedy P, Manriquez C, Myers SA, Crawford R, Faulkner GJ, Rao A. Sepulveda H, et al. bioRxiv [Preprint]. 2024 Jan 31:2024.01.31.578097. doi: 10.1101/2024.01.31.578097. bioRxiv. 2024. PMID: 38352366 Free PMC article. Preprint.
Subregional efforts to improve childhood cancer care in the Andean countries.
Calle MDC, Mallqui M, Beingolea L, Chavez F, Gallardo P, Vásquez L, Sepúlveda H. Calle MDC, et al. Among authors: sepulveda h. Rev Panam Salud Publica. 2023 Oct 15;47:e151. doi: 10.26633/RPSP.2023.151. eCollection 2023. Rev Panam Salud Publica. 2023. PMID: 37854495 Free PMC article.
85 results