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Page 1
Development of an inhalable antiviral powder formulation against respiratory syncytial virus.
Heida R, Akkerman R, Jacob Silva PH, Lakerveld AJ, Ortiz D, Bigogno C, Gasbarri M, van Kasteren PB, Stellacci F, Frijlink HW, Huckriede ALW, Hinrichs WLJ. Heida R, et al. Among authors: bigogno c. J Control Release. 2023 May;357:264-273. doi: 10.1016/j.jconrel.2023.03.059. Epub 2023 Apr 5. J Control Release. 2023. PMID: 37015293 Free article.
Development of N-(4-(1H-Imidazol-1-yl)phenyl)-4-chlorobenzenesulfonamide, a Novel Potent Inhibitor of β-Catenin with Enhanced Antitumor Activity and Metabolic Stability.
Puxeddu M, Ling L, Ripa S, D'Ambrosio M, Nalli M, Parisi A, Sciò P, Coluccia A, Granese A, Santelli M, Masci D, Cuřínová P, Naro C, Sette C, Pastore A, Stornaiuolo M, Bigogno C, Dondio G, Di Magno L, Canettieri G, Liu T, Silvestri R, La Regina G. Puxeddu M, et al. Among authors: bigogno c. J Med Chem. 2024 Nov 28;67(22):20298-20314. doi: 10.1021/acs.jmedchem.4c01708. Epub 2024 Nov 7. J Med Chem. 2024. PMID: 39508273
SAR Analysis of Novel Coxsackie virus A9 Capsid Binders.
Tammaro C, Plavec Z, Myllymäki L, Mitchell C, Consalvi S, Biava M, Ciogli A, Domanska A, Leppilampi V, Buckner C, Manetto S, Sciò P, Coluccia A, Laajala M, Dondio GM, Bigogno C, Marjomäki V, Butcher SJ, Poce G. Tammaro C, et al. Among authors: bigogno c. J Med Chem. 2024 Oct 10;67(19):17144-17161. doi: 10.1021/acs.jmedchem.4c00701. Epub 2024 Sep 18. J Med Chem. 2024. PMID: 39292620
4-(3-Phenylsulfonylindol-2-yl)-1-(pyridin-2-yl)piperazinyl-methanones as Potent Inhibitors of both SARS-CoV-2 and HCoV-OC43 Viruses.
Puxeddu M, Donalisio M, Bugert JJ, Corona A, Cocomazzi P, Milani M, Hucke F, Arduino I, Esposito F, Moretti P, Ortore MG, Nalli M, Manetto S, Mazzoccanti G, Bigogno C, Dondio G, Sciò P, Coluccia A, Fracella M, Antonelli G, Lembo D, Tramontano E, Silvestri R, Mastrangelo E, La Regina G. Puxeddu M, et al. Among authors: bigogno c. ACS Infect Dis. 2024 Sep 13;10(9):3158-3175. doi: 10.1021/acsinfecdis.4c00108. Epub 2024 Aug 3. ACS Infect Dis. 2024. PMID: 39096289
Novel N-(Heterocyclylphenyl)benzensulfonamide Sharing an Unreported Binding Site with T-Cell Factor 4 at the β-Catenin Armadillo Repeats Domain as an Anticancer Agent.
Nalli M, Di Magno L, Wen Y, Liu X, D'Ambrosio M, Puxeddu M, Parisi A, Sebastiani J, Sorato A, Coluccia A, Ripa S, Di Pastena F, Capelli D, Montanari R, Masci D, Urbani A, Naro C, Sette C, Orlando V, D'Angelo S, Biagioni S, Bigogno C, Dondio G, Pastore A, Stornaiuolo M, Canettieri G, Liu T, Silvestri R, La Regina G. Nalli M, et al. Among authors: bigogno c. ACS Pharmacol Transl Sci. 2023 Jul 3;6(7):1087-1103. doi: 10.1021/acsptsci.3c00092. eCollection 2023 Jul 14. ACS Pharmacol Transl Sci. 2023. PMID: 37470018 Free PMC article.
RS6077 induces mitotic arrest and selectively activates cell death in human cancer cell lines and in a lymphoma tumor in vivo.
Sebastiani J, Puxeddu M, Nalli M, Bai R, Altieri L, Rovella P, Gaudio E, Trisciuoglio D, Spriano F, Lavia P, Fionda C, Masci D, Urbani A, Bigogno C, Dondio G, Hamel E, Bertoni F, Silvestri R, La Regina G. Sebastiani J, et al. Among authors: bigogno c. Eur J Med Chem. 2023 Jan 15;246:114997. doi: 10.1016/j.ejmech.2022.114997. Epub 2022 Dec 5. Eur J Med Chem. 2023. PMID: 36502578
45 results