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Monitoring M-Protein, Therapeutic Antibodies, and Polyclonal Antibodies in a Multiparametric Mass Spectrometry Assay Provides Insight into Therapy Response Kinetics in Patients with Multiple Myeloma.
Wijnands C, Karel PGA, Gloerich J, Armony G, Tzasta A, de Kat Angelino CM, Di Stefano L, Bonifay V, Luider TM, VanDuijn MM, Croockewit SJ, de Kort EA, Castelijn DAR, Stege CAM, Wessels HJCT, van Gool AJ, van de Donk NWCJ, Jacobs JFM. Wijnands C, et al. Pharmaceutics. 2025 Jan 19;17(1):135. doi: 10.3390/pharmaceutics17010135. Pharmaceutics. 2025. PMID: 39861781
An automated workflow based on data independent acquisition for practical and high-throughput personalized assay development and minimal residual disease monitoring in multiple myeloma patients.
Wijnands C, Armony G, Noori S, Gloerich J, Bonifay V, Caillon H, Luider TM, Brehmer S, Pfennig L, Srikumar T, Trede D, Kruppa G, Dejoie T, van Duijn MM, van Gool AJ, Jacobs JFM, Wessels HJCT. Wijnands C, et al. Among authors: van duijn mm. Clin Chem Lab Med. 2024 Jun 17;62(12):2507-2518. doi: 10.1515/cclm-2024-0306. Print 2024 Nov 26. Clin Chem Lab Med. 2024. PMID: 38872409 Free article.
N-linked glycosylation of the M-protein variable region: glycoproteogenomics reveals a new layer of personalized complexity in multiple myeloma.
Langerhorst P, Baerenfaenger M, Kulkarni P, Nadal S, Wijnands C, Post MA, Noori S, vanDuijn MM, Joosten I, Dejoie T, van Gool AJ, Gloerich J, Lefeber DJ, Wessels HJCT, Jacobs JFM. Langerhorst P, et al. Clin Chem Lab Med. 2024 Feb 9;62(8):1626-1635. doi: 10.1515/cclm-2023-1189. Print 2024 Jul 26. Clin Chem Lab Med. 2024. PMID: 38332688 Free article.
M-protein diagnostics in multiple myeloma patients using ultra-sensitive targeted mass spectrometry and an off-the-shelf calibrator.
Wijnands C, Langerhorst P, Noori S, Keizer-Garritsen J, Wessels HJCT, Gloerich J, Bonifay V, Caillon H, Luider TM, van Gool AJ, Dejoie T, VanDuijn MM, Jacobs JFM. Wijnands C, et al. Clin Chem Lab Med. 2023 Oct 12;62(3):540-550. doi: 10.1515/cclm-2023-0781. Print 2024 Feb 26. Clin Chem Lab Med. 2023. PMID: 37823394 Free PMC article.
90 results