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RNA editing: Expanding the potential of RNA therapeutics.
Booth BJ, Nourreddine S, Katrekar D, Savva Y, Bose D, Long TJ, Huss DJ, Mali P. Booth BJ, et al. Among authors: mali p. Mol Ther. 2023 Jun 7;31(6):1533-1549. doi: 10.1016/j.ymthe.2023.01.005. Epub 2023 Jan 7. Mol Ther. 2023. PMID: 36620962 Free PMC article. Review.
A PERTURBATION CELL ATLAS OF HUMAN INDUCED PLURIPOTENT STEM CELLS.
Nourreddine S, Doctor Y, Dailamy A, Forget A, Lee YH, Chinn B, Khaliq H, Polacco B, Muralidharan M, Pan E, Zhang Y, Sigaeva A, Hansen JN, Gao J, Parker JA, Obernier K, Clark T, Chen JY, Metallo C, Lundberg E, Ideker T, Krogan N, Mali P. Nourreddine S, et al. Among authors: mali p. bioRxiv [Preprint]. 2024 Nov 4:2024.11.03.621734. doi: 10.1101/2024.11.03.621734. bioRxiv. 2024. PMID: 39574586 Free PMC article. Preprint.
Multimodal perturbation analyses of cyclin-dependent kinases reveal a network of synthetic lethalities associated with cell-cycle regulation and transcriptional regulation.
Ford K, Munson BP, Fong SH, Panwala R, Chu WK, Rainaldi J, Plongthongkum N, Arunachalam V, Kostrowicki J, Meluzzi D, Kreisberg JF, Jensen-Pergakes K, VanArsdale T, Paul T, Tamayo P, Zhang K, Bienkowska J, Mali P, Ideker T. Ford K, et al. Among authors: mali p. Sci Rep. 2023 May 11;13(1):7678. doi: 10.1038/s41598-023-33329-2. Sci Rep. 2023. PMID: 37169829 Free PMC article.
Interface-guided phenotyping of coding variants in the transcription factor RUNX1.
Ozturk K, Panwala R, Sheen J, Ford K, Jayne N, Portell A, Zhang DE, Hutter S, Haferlach T, Ideker T, Mali P, Carter H. Ozturk K, et al. Among authors: mali p. Cell Rep. 2024 Jul 23;43(7):114436. doi: 10.1016/j.celrep.2024.114436. Epub 2024 Jul 4. Cell Rep. 2024. PMID: 38968069 Free PMC article.
A genome-wide CRISPR screen reveals that antagonism of glutamine metabolism sensitizes head and neck squamous cell carcinoma to ferroptotic cell death.
Allevato MM, Trinh S, Koshizuka K, Nachmanson D, Nguyen TC, Yokoyama Y, Wu X, Andres A, Wang Z, Watrous J, Molinolo AA, Mali P, Harismendy O, Jain M, Wild R, Gutkind JS. Allevato MM, et al. Among authors: mali p. Cancer Lett. 2024 Aug 28;598:217089. doi: 10.1016/j.canlet.2024.217089. Epub 2024 Jul 2. Cancer Lett. 2024. PMID: 38964731
Transcriptional control of leukemogenesis by the chromatin reader SGF29.
Barbosa K, Deshpande A, Perales M, Xiang P, Murad R, Pramod AB, Minkina A, Robertson N, Schischlik F, Lei X, Sun Y, Brown A, Amend D, Jeremias I, Doench JG, Humphries RK, Ruppin E, Shendure J, Mali P, Adams PD, Deshpande AJ. Barbosa K, et al. Among authors: mali p. Blood. 2024 Feb 22;143(8):697-712. doi: 10.1182/blood.2023021234. Blood. 2024. PMID: 38048593
193 results