Zheng S - Search Results

1

Targeting ANGPTL3 by GalNAc-conjugated siRNA ANGsiR10 lowers blood lipids with long-lasting and potent efficacy in mice and monkeys.

Wang J, Zheng W, Zheng S, Yuan Y, Wen W, Cui W, Xue L, Sun X, Shang H, Zhang H, Xiao RP, Gao S, Zhang X. Wang J, et al. Among authors: zheng s, zheng w. Mol Ther Nucleic Acids. 2022 Dec 5;31:68-77. doi: 10.1016/j.omtn.2022.11.023. eCollection 2023 Mar 14. Mol Ther Nucleic Acids. 2022. PMID: 36618267 Free PMC article.

2

Elimination pathways of systemically delivered siRNA.

Huang Y, Hong J, Zheng S, Ding Y, Guo S, Zhang H, Zhang X, Du Q, Liang Z. Huang Y, et al. Among authors: zheng s. Mol Ther. 2011 Feb;19(2):381-5. doi: 10.1038/mt.2010.266. Epub 2010 Nov 30. Mol Ther. 2011. PMID: 21119623 Free PMC article.

3

Binary and ternary complexes based on polycaprolactone-graft-poly (N, N-dimethylaminoethyl methacrylate) for targeted siRNA delivery.

Huang Y, Lin D, Jiang Q, Zhang W, Guo S, Xiao P, Zheng S, Wang X, Chen H, Zhang HY, Deng L, Xing J, Du Q, Dong A, Liang Z. Huang Y, et al. Among authors: zheng s. Biomaterials. 2012 Jun;33(18):4653-64. doi: 10.1016/j.biomaterials.2012.02.052. Epub 2012 Apr 3. Biomaterials. 2012. PMID: 22480869

4

The effect of guanidinylation of PEGylated poly(2-aminoethyl methacrylate) on the systemic delivery of siRNA.

Cheng Q, Huang Y, Zheng H, Wei T, Zheng S, Huo S, Wang X, Du Q, Zhang X, Zhang HY, Liang XJ, Wang C, Tang R, Liang Z. Cheng Q, et al. Among authors: zheng s, zheng h. Biomaterials. 2013 Apr;34(12):3120-31. doi: 10.1016/j.biomaterials.2013.01.043. Epub 2013 Feb 1. Biomaterials. 2013. PMID: 23375954

5

Systemic and tumor-targeted delivery of siRNA by cyclic NGR and isoDGR motif-containing peptides.

Huang Y, Cheng Q, Jin X, Ji JL, Guo S, Zheng S, Wang X, Cao H, Gao S, Liang XJ, Du Q, Liang Z. Huang Y, et al. Among authors: zheng s. Biomater Sci. 2016 Mar;4(3):494-510. doi: 10.1039/c5bm00429b. Biomater Sci. 2016. PMID: 26783563

6

Pharmacokinetic Behaviors of Intravenously Administered siRNA in Glandular Tissues.

Huang Y, Cheng Q, Ji JL, Zheng S, Du L, Meng L, Wu Y, Zhao D, Wang X, Lai L, Cao H, Xiao K, Gao S, Liang Z. Huang Y, et al. Among authors: zheng s. Theranostics. 2016 Jun 18;6(10):1528-41. doi: 10.7150/thno.15246. eCollection 2016. Theranostics. 2016. PMID: 27446488 Free PMC article.

7

siRNA Knockdown of RRM2 Effectively Suppressed Pancreatic Tumor Growth Alone or Synergistically with Doxorubicin.

Zheng S, Wang X, Weng YH, Jin X, Ji JL, Guo L, Hu B, Liu N, Cheng Q, Zhang J, Bai H, Yang T, Xia XH, Zhang HY, Gao S, Huang Y. Zheng S, et al. Mol Ther Nucleic Acids. 2018 Sep 7;12:805-816. doi: 10.1016/j.omtn.2018.08.003. Epub 2018 Aug 8. Mol Ther Nucleic Acids. 2018. PMID: 30153565 Free PMC article.

8

Ionizable liposomal siRNA therapeutics enables potent and persistent treatment of Hepatitis B.

Huang Y, Zheng S, Guo Z, de Mollerat du Jeu X, Liang XJ, Yang Z, Zhang HY, Gao S, Liang Z. Huang Y, et al. Among authors: zheng s. Signal Transduct Target Ther. 2022 Feb 11;7(1):38. doi: 10.1038/s41392-021-00859-y. Signal Transduct Target Ther. 2022. PMID: 35145057 Free PMC article.

9

Analysis of the pharmacokinetics and efficacy of RBD1016 - A GalNAc-siRNA targeting Hepatitis B Virus X gene using semi-mechanistic PK/PD model.

Li Q, Geng T, Li H, Zheng S, Svedlund S, Gan L, Egnell AC, Gao S, Chen R, Hu P. Li Q, et al. Among authors: zheng s. Heliyon. 2024 May 24;10(11):e31924. doi: 10.1016/j.heliyon.2024.e31924. eCollection 2024 Jun 15. Heliyon. 2024. PMID: 38841435 Free PMC article.

10

Inter-molecular β-sheet structure facilitates lung-targeting siRNA delivery.

Zhou J, Li D, Wen H, Zheng S, Su C, Yi F, Wang J, Liang Z, Tang T, Zhou D, Zhang LH, Liang D, Du Q. Zhou J, et al. Among authors: zheng s. Sci Rep. 2016 Mar 9;6:22731. doi: 10.1038/srep22731. Sci Rep. 2016. PMID: 26955887 Free PMC article.

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