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Outer membrane permeabilization by the membrane attack complex sensitizes Gram-negative bacteria to antimicrobial proteins in serum and phagocytes.
Heesterbeek DAC, Muts RM, van Hensbergen VP, de Saint Aulaire P, Wennekes T, Bardoel BW, van Sorge NM, Rooijakkers SHM. Heesterbeek DAC, et al. Among authors: muts rm. PLoS Pathog. 2021 Jan 22;17(1):e1009227. doi: 10.1371/journal.ppat.1009227. eCollection 2021 Jan. PLoS Pathog. 2021. PMID: 33481964 Free PMC article.
CD5L is a canonical component of circulatory IgM.
Oskam N, den Boer MA, Lukassen MV, Ooijevaar-de Heer P, Veth TS, van Mierlo G, Lai SH, Derksen NIL, Yin V, Streutker M, Franc V, Šiborová M, Damen MJA, Kos D, Barendregt A, Bondt A, van Goudoever JB, de Haas CJC, Aerts PC, Muts RM, Rooijakkers SHM, Vidarsson G, Rispens T, Heck AJR. Oskam N, et al. Among authors: muts rm. Proc Natl Acad Sci U S A. 2023 Dec 12;120(50):e2311265120. doi: 10.1073/pnas.2311265120. Epub 2023 Dec 6. Proc Natl Acad Sci U S A. 2023. PMID: 38055740 Free PMC article.
Single-cell Sequencing of Circulating Human Plasmablasts during Staphylococcus aureus Bacteremia.
Kerkman PF, de Vor L, van der Vaart TW, Ten Doesschate T, Muts RM, Depelteau JS, Scheepmaker LM, Ruyken M, de Haas CJC, Aerts PC, Marijnissen RJ, Schuurman J, Beurskens FJ, Gorlani A, Bardoel BW, Rooijakkers SHM. Kerkman PF, et al. Among authors: muts rm. J Immunol. 2024 Dec 1;213(11):1644-1655. doi: 10.4049/jimmunol.2300858. J Immunol. 2024. PMID: 39451041 Free PMC article.
Agnostic B cell selection approach identifies antibodies against K. pneumoniae that synergistically drive complement activation.
van der Lans SPA, Bardoel BW, Ruyken M, de Haas CJC, Baijens S, Muts RM, Scheepmaker LM, Aerts PC, van 't Wout MFL, Preiner J, Marijnissen RJ, Schuurman J, Beurskens FJ, Kerkman PF, Rooijakkers SHM. van der Lans SPA, et al. Among authors: muts rm. Nat Commun. 2024 Sep 16;15(1):8100. doi: 10.1038/s41467-024-52372-9. Nat Commun. 2024. PMID: 39285158 Free PMC article.