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CD74 is expressed in a subset of pediatric acute myeloid leukemia patients and is a promising target for therapy: a report from the Children's Oncology Group.
Menssen AJ, Hudson CA, Alonzo T, Gerbing R, Pardo L, Leonti A, Cook JA, Hsu FC, Lott LL, Dai F, Fearing C, Ghirardelli K, Hylkema T, Tarlock K, Loeb KR, Kolb EA, Cooper T, Pollard J, Wells DA, Loken MR, Aplenc R, Meshinchi S, Brodersen LE. Menssen AJ, et al. Among authors: brodersen le. Haematologica. 2024 Oct 1;109(10):3182-3193. doi: 10.3324/haematol.2023.283757. Haematologica. 2024. PMID: 38299667 Free PMC article.
A longitudinal single-cell atlas of treatment response in pediatric AML.
Lambo S, Trinh DL, Ries RE, Jin D, Setiadi A, Ng M, Leblanc VG, Loken MR, Brodersen LE, Dai F, Pardo LM, Ma X, Vercauteren SM, Meshinchi S, Marra MA. Lambo S, et al. Among authors: brodersen le. Cancer Cell. 2023 Dec 11;41(12):2117-2135.e12. doi: 10.1016/j.ccell.2023.10.008. Epub 2023 Nov 16. Cancer Cell. 2023. PMID: 37977148 Free article.
The impact of Down syndrome-specific non-malignant hematopoietic regeneration in the bone marrow on the detection of leukemic measurable residual disease.
Hsu FC, Hudson C, Wilson ER, Pardo LM, Singleton TP, Xu D, Zehentner BK, Hitzler J, Berman J, Wells DA, Loken MR, Brodersen LE. Hsu FC, et al. Among authors: brodersen le. Cytometry B Clin Cytom. 2023 Jul;104(4):311-318. doi: 10.1002/cyto.b.22118. Epub 2023 Apr 4. Cytometry B Clin Cytom. 2023. PMID: 37015883 Free article.
Comprehensive molecular and clinical characterization of NUP98 fusions in pediatric acute myeloid leukemia.
Bertrums EJM, Smith JL, Harmon L, Ries RE, Wang YJ, Alonzo TA, Menssen AJ, Chisholm KM, Leonti AR, Tarlock K, Ostronoff F, Pogosova-Agadjanyan EL, Kaspers GJL, Hasle H, Dworzak M, Walter C, Muhlegger N, Morerio C, Pardo L, Hirsch B, Raimondi S, Cooper TM, Aplenc R, Gamis AS, Kolb EA, Farrar JE, Stirewalt D, Ma X, Shaw TI, Furlan SN, Brodersen LE, Loken MR, Van den Heuvel-Eibrink MM, Zwaan CM, Triche TJ, Goemans BF, Meshinchi S. Bertrums EJM, et al. Among authors: brodersen le. Haematologica. 2023 Aug 1;108(8):2044-2058. doi: 10.3324/haematol.2022.281653. Haematologica. 2023. PMID: 36815378 Free PMC article.
Preclinical studies targeting CD74 with STRO-001 antibody-drug conjugate in acute leukemia.
Le Q, Tang T, Leonti A, Castro S, McKay CN, Perkins L, Pardo L, Kirkey D, Hylkema T, Call L, Manselle M, Abrahams C, Bedard K, Molina A, Brodersen LE, Loken MR, Tarlock K, Meshinchi S, Loeb KR. Le Q, et al. Among authors: brodersen le. Blood Adv. 2023 May 9;7(9):1666-1670. doi: 10.1182/bloodadvances.2022008303. Blood Adv. 2023. PMID: 36595452 Free PMC article. No abstract available.
Multicenter prospective evaluation of diagnostic potential of flow cytometric aberrancies in myelodysplastic syndromes by the ELN iMDS flow working group.
Kern W, Westers TM, Bellos F, Bene MC, Bettelheim P, Brodersen LE, Burbury K, Chu SC, Cullen M, Porta MD, Dunlop AS, Johansson U, Matarraz S, Oelschlaegel U, Ogata K, Porwit A, Preijers F, Psarra K, Saft L, Subirá D, Weiß E, van der Velden VHJ, van de Loosdrecht A. Kern W, et al. Among authors: brodersen le. Cytometry B Clin Cytom. 2023 Jan;104(1):51-65. doi: 10.1002/cyto.b.22105. Epub 2022 Nov 23. Cytometry B Clin Cytom. 2023. PMID: 36416672 Free article.
Targeting FOLR1 in high-risk CBF2AT3-GLIS2 pediatric AML with STRO-002 FOLR1-antibody-drug conjugate.
Tang T, Le Q, Castro S, Pardo L, McKay CN, Perkins L, Smith J, Kirkey D, Abrahams C, Bedard K, Molina A, Brodersen LE, Loken MR, Tarlock K, Meshinchi S, Loeb KR. Tang T, et al. Among authors: brodersen le. Blood Adv. 2022 Nov 22;6(22):5933-5937. doi: 10.1182/bloodadvances.2022008503. Blood Adv. 2022. PMID: 36149945 Free PMC article. No abstract available.
Therapeutic targeting of PRAME with mTCRCAR T cells in acute myeloid leukemia.
Kirkey DC, Loeb AM, Castro S, McKay CN, Perkins L, Pardo L, Leonti AR, Tang TT, Loken MR, Brodersen LE, Loeb KR, Scheinberg DA, Le Q, Meshinchi S. Kirkey DC, et al. Among authors: brodersen le. Blood Adv. 2023 Apr 11;7(7):1178-1189. doi: 10.1182/bloodadvances.2022008304. Blood Adv. 2023. PMID: 35984639 Free PMC article.
Sorafenib in Combination With Standard Chemotherapy for Children With High Allelic Ratio FLT3/ITD+ Acute Myeloid Leukemia: A Report From the Children's Oncology Group Protocol AAML1031.
Pollard JA, Alonzo TA, Gerbing R, Brown P, Fox E, Choi J, Fisher B, Hirsch B, Kahwash S, Getz K, Levine J, Brodersen LE, Loken MR, Raimondi S, Tarlock K, Wood A, Sung L, Kolb EA, Gamis A, Meshinchi S, Aplenc R. Pollard JA, et al. Among authors: brodersen le. J Clin Oncol. 2022 Jun 20;40(18):2023-2035. doi: 10.1200/JCO.21.01612. Epub 2022 Mar 29. J Clin Oncol. 2022. PMID: 35349331 Free PMC article.
Integrated analysis of genotype and phenotype reveals clonal evolution and cytogenetically driven disruption of myeloid cell maturation in myelodysplastic syndromes.
Cutler JA, Pugsley HR, Bennington R, Fritschle W, Hartmann L, Zaidi N, Menssen AJ, Singleton TP, Xu D, Loken MR, Wells DA, Brodersen LE, Zehentner BK. Cutler JA, et al. Among authors: brodersen le. Cytometry B Clin Cytom. 2023 Mar;104(2):183-194. doi: 10.1002/cyto.b.22036. Epub 2021 Nov 13. Cytometry B Clin Cytom. 2023. PMID: 34773362 Free article.
24 results