Ruiz M - Search Results

1

Elevated Adipocyte Membrane Phospholipid Saturation Does Not Compromise Insulin Signaling.

Palmgren H, Petkevicius K, Bartesaghi S, Ahnmark A, Ruiz M, Nilsson R, Löfgren L, Glover MS, Andréasson AC, Andersson L, Becquart C, Kurczy M, Kull B, Wallin S, Karlsson D, Hess S, Maresca M, Bohlooly-Y M, Peng XR, Pilon M. Palmgren H, et al. Among authors: ruiz m. Diabetes. 2023 Oct 1;72(10):1350-1363. doi: 10.2337/db22-0293. Diabetes. 2023. PMID: 36580483 Free PMC article.

2

The adiponectin receptor AdipoR2 and its Caenorhabditis elegans homolog PAQR-2 prevent membrane rigidification by exogenous saturated fatty acids.

Devkota R, Svensk E, Ruiz M, Ståhlman M, Borén J, Pilon M. Devkota R, et al. Among authors: ruiz m. PLoS Genet. 2017 Sep 8;13(9):e1007004. doi: 10.1371/journal.pgen.1007004. eCollection 2017 Sep. PLoS Genet. 2017. PMID: 28886012 Free PMC article.

3

Membrane Fluidity Is Regulated Cell Nonautonomously by Caenorhabditiselegans PAQR-2 and Its Mammalian Homolog AdipoR2.

Bodhicharla R, Devkota R, Ruiz M, Pilon M. Bodhicharla R, et al. Among authors: ruiz m. Genetics. 2018 Sep;210(1):189-201. doi: 10.1534/genetics.118.301272. Epub 2018 Jul 11. Genetics. 2018. PMID: 29997234 Free PMC article.

4

Membrane fluidity is regulated by the C. elegans transmembrane protein FLD-1 and its human homologs TLCD1/2.

Ruiz M, Bodhicharla R, Svensk E, Devkota R, Busayavalasa K, Palmgren H, Ståhlman M, Boren J, Pilon M. Ruiz M, et al. Elife. 2018 Dec 4;7:e40686. doi: 10.7554/eLife.40686. Elife. 2018. PMID: 30509349 Free PMC article.

5

AdipoR1 and AdipoR2 maintain membrane fluidity in most human cell types and independently of adiponectin.

Ruiz M, Ståhlman M, Borén J, Pilon M. Ruiz M, et al. J Lipid Res. 2019 May;60(5):995-1004. doi: 10.1194/jlr.M092494. Epub 2019 Mar 19. J Lipid Res. 2019. PMID: 30890562 Free PMC article.

6

Evolutionarily conserved long-chain Acyl-CoA synthetases regulate membrane composition and fluidity.

Ruiz M, Bodhicharla R, Ståhlman M, Svensk E, Busayavalasa K, Palmgren H, Ruhanen H, Boren J, Pilon M. Ruiz M, et al. Elife. 2019 Nov 26;8:e47733. doi: 10.7554/eLife.47733. Elife. 2019. PMID: 31769755 Free PMC article.

7

Leveraging a gain-of-function allele of Caenorhabditis elegans paqr-1 to elucidate membrane homeostasis by PAQR proteins.

Busayavalasa K, Ruiz M, Devkota R, Ståhlman M, Bodhicharla R, Svensk E, Hermansson NO, Borén J, Pilon M. Busayavalasa K, et al. Among authors: ruiz m. PLoS Genet. 2020 Aug 4;16(8):e1008975. doi: 10.1371/journal.pgen.1008975. eCollection 2020 Aug. PLoS Genet. 2020. PMID: 32750056 Free PMC article.

8

Extensive transcription mis-regulation and membrane defects in AdipoR2-deficient cells challenged with saturated fatty acids.

Ruiz M, Palmgren H, Henricsson M, Devkota R, Jaiswal H, Maresca M, Bohlooly-Y M, Peng XR, Borén J, Pilon M. Ruiz M, et al. Biochim Biophys Acta Mol Cell Biol Lipids. 2021 Apr;1866(4):158884. doi: 10.1016/j.bbalip.2021.158884. Epub 2021 Jan 11. Biochim Biophys Acta Mol Cell Biol Lipids. 2021. PMID: 33444759 Free article.

9

Palmitic acid causes increased dihydroceramide levels when desaturase expression is directly silenced or indirectly lowered by silencing AdipoR2.

Ruiz M, Henricsson M, Borén J, Pilon M. Ruiz M, et al. Lipids Health Dis. 2021 Nov 28;20(1):173. doi: 10.1186/s12944-021-01600-y. Lipids Health Dis. 2021. PMID: 34839823 Free PMC article.

10

A small molecule screen for paqr-2 suppressors identifies Tyloxapol as a membrane fluidizer for C. elegans and mammalian cells.

Ruiz M, Svensk E, Einarsson E, Grahn EP, Pilon M. Ruiz M, et al. Biochim Biophys Acta Biomembr. 2022 Sep 1;1864(9):183959. doi: 10.1016/j.bbamem.2022.183959. Epub 2022 May 17. Biochim Biophys Acta Biomembr. 2022. PMID: 35588889 Free article.

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