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Page 1
Natural selection of immune and metabolic genes associated with health in two lowland Bolivian populations.
Lea AJ, Garcia A, Arevalo J, Ayroles JF, Buetow K, Cole SW, Eid Rodriguez D, Gutierrez M, Highland HM, Hooper PL, Justice A, Kraft T, North KE, Stieglitz J, Kaplan H, Trumble BC, Gurven MD. Lea AJ, et al. Among authors: ayroles jf. Proc Natl Acad Sci U S A. 2023 Jan 3;120(1):e2207544120. doi: 10.1073/pnas.2207544120. Epub 2022 Dec 27. Proc Natl Acad Sci U S A. 2023. PMID: 36574663 Free PMC article.
Epistasis dominates the genetic architecture of Drosophila quantitative traits.
Huang W, Richards S, Carbone MA, Zhu D, Anholt RR, Ayroles JF, Duncan L, Jordan KW, Lawrence F, Magwire MM, Warner CB, Blankenburg K, Han Y, Javaid M, Jayaseelan J, Jhangiani SN, Muzny D, Ongeri F, Perales L, Wu YQ, Zhang Y, Zou X, Stone EA, Gibbs RA, Mackay TF. Huang W, et al. Among authors: ayroles jf. Proc Natl Acad Sci U S A. 2012 Sep 25;109(39):15553-9. doi: 10.1073/pnas.1213423109. Epub 2012 Sep 4. Proc Natl Acad Sci U S A. 2012. PMID: 22949659 Free PMC article.
Genetic and environmental perturbations lead to regulatory decoherence.
Lea A, Subramaniam M, Ko A, Lehtimäki T, Raitoharju E, Kähönen M, Seppälä I, Mononen N, Raitakari OT, Ala-Korpela M, Pajukanta P, Zaitlen N, Ayroles JF. Lea A, et al. Among authors: ayroles jf. Elife. 2019 Mar 5;8:e40538. doi: 10.7554/eLife.40538. Elife. 2019. PMID: 30834892 Free PMC article.
Socioeconomic status effects on health vary between rural and urban Turkana.
Lea AJ, Waigwa C, Muhoya B, Lotukoi F, Peng J, Henry LP, Abhyankar V, Kamau J, Martins D, Gurven M, Ayroles JF. Lea AJ, et al. Among authors: ayroles jf. Evol Med Public Health. 2021 Nov 25;9(1):406-419. doi: 10.1093/emph/eoab039. eCollection 2021. Evol Med Public Health. 2021. PMID: 34987823 Free PMC article.
Characterizing the landscape of gene expression variance in humans.
Wolf S, Melo D, Garske KM, Pallares LF, Lea AJ, Ayroles JF. Wolf S, et al. Among authors: ayroles jf. PLoS Genet. 2023 Jul 6;19(7):e1010833. doi: 10.1371/journal.pgen.1010833. eCollection 2023 Jul. PLoS Genet. 2023. PMID: 37410774 Free PMC article.
55 results