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Page 1
Ectopic expression of DNMT3L in human trophoblast stem cells restores features of the placental methylome.
Lea G, Doria-Borrell P, Ferrero-Micó A, Varma A, Simon C, Anderson H, Biggins L, De Clercq K, Andrews S, Niakan KK, Gahurova L, McGovern N, Pérez-García V, Hanna CW. Lea G, et al. Among authors: biggins l. Cell Stem Cell. 2024 Dec 31:S1934-5909(24)00447-8. doi: 10.1016/j.stem.2024.12.007. Online ahead of print. Cell Stem Cell. 2024. PMID: 39788122 Free article.
The receptor protein tyrosine phosphatase PTPRK promotes intestinal repair and catalysis-independent tumour suppression.
Young KA, Wojdyla K, Lai T, Mulholland KE, Aldaz Casanova S, Antrobus R, Andrews SR, Biggins L, Mahler-Araujo B, Barton PR, Anderson KR, Fearnley GW, Sharpe HJ. Young KA, et al. Among authors: biggins l. J Cell Sci. 2024 Jul 15;137(14):jcs261914. doi: 10.1242/jcs.261914. Epub 2024 Jul 22. J Cell Sci. 2024. PMID: 38904097 Free PMC article.
The tissue-resident regulatory T cell pool is shaped by transient multi-tissue migration and a conserved residency program.
Burton OT, Bricard O, Tareen S, Gergelits V, Andrews S, Biggins L, Roca CP, Whyte C, Junius S, Brajic A, Pasciuto E, Ali M, Lemaitre P, Schlenner SM, Ishigame H, Brown BD, Dooley J, Liston A. Burton OT, et al. Among authors: biggins l. Immunity. 2024 Jul 9;57(7):1586-1602.e10. doi: 10.1016/j.immuni.2024.05.023. Epub 2024 Jun 18. Immunity. 2024. PMID: 38897202 Free article.
Native Size-Exclusion Chromatography-Based Mass Spectrometry Reveals New Components of the Early Heat Shock Protein 90 Inhibition Response Among Limited Global Changes.
Samant RS, Batista S, Larance M, Ozer B, Milton CI, Bludau I, Wu E, Biggins L, Andrews S, Hervieu A, Johnston HE, Al-Lazikhani B, Lamond AI, Clarke PA, Workman P. Samant RS, et al. Among authors: biggins l. Mol Cell Proteomics. 2023 Feb;22(2):100485. doi: 10.1016/j.mcpro.2022.100485. Epub 2022 Dec 20. Mol Cell Proteomics. 2023. PMID: 36549590 Free PMC article.
Integrated multi-omics reveal polycomb repressive complex 2 restricts human trophoblast induction.
Zijlmans DW, Talon I, Verhelst S, Bendall A, Van Nerum K, Javali A, Malcolm AA, van Knippenberg SSFA, Biggins L, To SK, Janiszewski A, Admiraal D, Knops R, Corthout N, Balaton BP, Georgolopoulos G, Panda A, Bhanu NV, Collier AJ, Fabian C, Allsop RN, Chappell J, Pham TXA, Oberhuemer M, Ertekin C, Vanheer L, Athanasouli P, Lluis F, Deforce D, Jansen JH, Garcia BA, Vermeulen M, Rivron N, Dhaenens M, Marks H, Rugg-Gunn PJ, Pasque V. Zijlmans DW, et al. Among authors: biggins l. Nat Cell Biol. 2022 Jun;24(6):858-871. doi: 10.1038/s41556-022-00932-w. Epub 2022 Jun 13. Nat Cell Biol. 2022. PMID: 35697783 Free PMC article.
Protein tyrosine phosphatases in cell adhesion.
Young KA, Biggins L, Sharpe HJ. Young KA, et al. Among authors: biggins l. Biochem J. 2021 Mar 12;478(5):1061-1083. doi: 10.1042/BCJ20200511. Biochem J. 2021. PMID: 33710332 Free PMC article. Review.