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PHASE 2 RANDOMIZED STUDY (ORION-1) OF A NOVEL, BIODEGRADABLE DEXAMETHASONE IMPLANT (AR-1105) FOR THE TREATMENT OF MACULAR EDEMA DUE TO CENTRAL OR BRANCH RETINAL VEIN OCCLUSION.
Singer MA, Boyer DS, Williams S, McKee H, Kerr K, Pegoraro T, Trevino L, Kopczynski CC, Hollander DA. Singer MA, et al. Among authors: williams s. Retina. 2023 Jan 1;43(1):25-33. doi: 10.1097/IAE.0000000000003632. Epub 2022 Oct 14. Retina. 2023. PMID: 36542081 Free PMC article. Clinical Trial.
Discovery and Preclinical Development of Novel Intraocular Pressure-Lowering Rho Kinase Inhibitor: Corticosteroid Conjugates.
Sturdivant J, Williams SS, Ina M, Weksler M, McDougal A, Clancy D, deLong MA, Girouard N, Zaretskaia M, Brennan K, Glendenning A, Foley B, Lin CW, White JC, Kopczynski C, Kelly CR. Sturdivant J, et al. Among authors: williams ss. J Ocul Pharmacol Ther. 2023 Mar;39(2):117-127. doi: 10.1089/jop.2022.0129. Epub 2023 Jan 4. J Ocul Pharmacol Ther. 2023. PMID: 36602977
Eyes on Topical Ocular Disposition: The Considered Design of a Lead Janus Kinase (JAK) Inhibitor That Utilizes a Unique Azetidin-3-Amino Bridging Scaffold to Attenuate Off-Target Kinase Activity, While Driving Potency and Aqueous Solubility.
Gordhan HM, Miller ST, Clancy DC, Ina M, McDougal AV, Cutno DK, Brown RV, Lichorowic CL, Sturdivant JM, Vick KA, Williams SS, deLong MA, White JC, Kopczynski CC, Ellis DA. Gordhan HM, et al. Among authors: williams ss. J Med Chem. 2023 Jul 13;66(13):8929-8950. doi: 10.1021/acs.jmedchem.3c00519. Epub 2023 Jun 14. J Med Chem. 2023. PMID: 37314941
The effects of ultra-selective beta1-antagonism on the metabolic and cytokine profile in septic shock patients receiving noradrenaline: a sub-investigation from the STRESS-L Randomised Study.
Thomas JL, McGee KC, Hossain A, Perkins GD, Gordon AC, Young D, McAuley D, Singer M, Lall R, Kramaric T, Lord JM, Whitehouse T, Mur LAJ; STRESS-L. collaborators. Thomas JL, et al. Intensive Care Med Exp. 2025 Jan 22;13(1):9. doi: 10.1186/s40635-024-00708-6. Intensive Care Med Exp. 2025. PMID: 39841388
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