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Page 1
Senescence Induced by UVB in Keratinocytes Impairs Amino Acids Balance.
Bauwens E, Parée T, Meurant S, Bouriez I, Hannart C, Wéra AC, Khelfi A, Fattaccioli A, Burteau S, Demazy C, Fransolet M, De Schutter C, Martin N, Théry J, Decanter G, Penel N, Bury M, Pluquet O, Garmyn M, Debacq-Chainiaux F. Bauwens E, et al. Among authors: penel n. J Invest Dermatol. 2023 Apr;143(4):554-565.e9. doi: 10.1016/j.jid.2022.11.017. Epub 2022 Dec 15. J Invest Dermatol. 2023. PMID: 36528129 Free article.
Erdafitinib in patients with advanced solid tumours with FGFR alterations (RAGNAR): an international, single-arm, phase 2 study.
Pant S, Schuler M, Iyer G, Witt O, Doi T, Qin S, Tabernero J, Reardon DA, Massard C, Minchom A, Lugowska I, Carranza O, Arnold D, Gutierrez M, Winter H, Stuyckens K, Crow L, Najmi S, Hammond C, Thomas S, Santiago-Walker A, Triantos S, Sweiti H, Loriot Y; RAGNAR Investigators. Pant S, et al. Lancet Oncol. 2023 Aug;24(8):925-935. doi: 10.1016/S1470-2045(23)00275-9. Lancet Oncol. 2023. PMID: 37541273 Free PMC article. Clinical Trial.
Heritable defects in telomere and mitotic function selectively predispose to sarcomas.
Ballinger ML, Pattnaik S, Mundra PA, Zaheed M, Rath E, Priestley P, Baber J, Ray-Coquard I, Isambert N, Causeret S, van der Graaf WTA, Puri A, Duffaud F, Le Cesne A, Seddon B, Chandrasekar C, Schiffman JD, Brohl AS, James PA, Kurtz JE, Penel N, Myklebost O, Meza-Zepeda LA, Pickett H, Kansara M, Waddell N, Kondrashova O, Pearson JV, Barbour AP, Li S, Nguyen TL, Fatkin D, Graham RM, Giannoulatou E, Green MJ, Kaplan W, Ravishankar S, Copty J, Powell JE, Cuppen E, van Eijk K, Veldink J, Ahn JH, Kim JE, Randall RL, Tucker K, Judson I, Sarin R, Ludwig T, Genin E, Deleuze JF; French Exome Project Consortium; Haber M, Marshall G, Cairns MJ, Blay JY; International Sarcoma Kindred Study; Thomas DM, Tattersall M, Neuhaus S, Lewis C, Tucker K, Carey-Smith R, Wood D, Porceddu S, Dickinson I, Thorne H, James P, Ray-Coquard I, Blay JY, Cassier P, Le Cesne A, Duffaud F, Penel N, Isambert N, Kurtz JE, Puri A, Sarin R, Ahn JH, Kim JE, Ward I, Judson I, van der Graaf W, Seddon B, Chandrasekar C, Rickar R, Hennig I, Schiffman J, Randall RL, Silvestri A, Zaratzian A, Tayao M, Walwyn K, Niedermayr E, Mang D, Clark R, Thorpe T, MacDonald J, Riddell K, Mar J, Fennelly V, Wicht A, Zielony B,… See abstract for full author list ➔ Ballinger ML, et al. Among authors: penel n. Science. 2023 Jan 20;379(6629):253-260. doi: 10.1126/science.abj4784. Epub 2023 Jan 19. Science. 2023. PMID: 36656928
Identification of HMGA2 as a predictive biomarker of response to bintrafusp alfa in a phase 1 trial in patients with advanced triple-negative breast cancer.
Spira A, Awada A, Isambert N, Lorente D, Penel N, Zhang Y, Ojalvo LS, Hicking C, Rolfe PA, Ihling C, Dussault I, Locke G, Borel C. Spira A, et al. Among authors: penel n. Front Oncol. 2022 Dec 8;12:981940. doi: 10.3389/fonc.2022.981940. eCollection 2022. Front Oncol. 2022. PMID: 36568239 Free PMC article.
Emergence of Neuroendocrine Tumors in Patients Treated with Androgen Receptor Pathway Inhibitors for Metastatic Prostate Cancer: A Systematic Review and Meta-analysis.
Séguier D, Parent P, Duterque-Coquillaud M, Labreuche J, Fromont-Hankard G, Dariane C, Penel N, Villers A, Turpin A, Olivier J. Séguier D, et al. Among authors: penel n. Eur Urol Oncol. 2025 Jan 16:S2588-9311(24)00297-9. doi: 10.1016/j.euo.2024.12.014. Online ahead of print. Eur Urol Oncol. 2025. PMID: 39824723 Review.
Sarcomas developed in patients with Lynch Syndrome are enriched in pleomorphic soft-tissue sarcomas and are sensitive to immunotherapy.
Poumeaud F, Valentin T, Fares N, Segier B, Watson S, Verret B, Tlemsani C, Penel N, Lejeune S, Firmin N, Sabouret A, Thery JC, Bonvalot S, Cottereau E, Cauchin E, Lancon A, Nambot S, Zattara H, Coudert M, Fourme E, Nogues C, Tougeron D, Prieur F, Collonge-Rame MA, Denis C, Laurent-Puig P, Chieze-Valero S, Dreyfus H, Jaffrelot M, Vande Perre P, Rochaix P, Gomez-Mascard A, Rochefort P, Campoy S, Chibon F, Lasset C, Selves J, Guimbaud R. Poumeaud F, et al. Among authors: penel n. Eur J Cancer. 2024 Dec 21;216:115196. doi: 10.1016/j.ejca.2024.115196. Online ahead of print. Eur J Cancer. 2024. PMID: 39742560
Preoperative versus postoperative radiotherapy for localized soft tissue sarcoma treated with curative intent in a French tertiary center "SARCLOC".
Noeuveglise M, Tessier W, Barthoulot M, Decanter G, Cayeux A, Marin H, Lemoine-Gobert P, Aymes E, Taieb S, Fayard C, Beaujot J, Robin YM, Lartigau EF, Penel N, Cordoba A. Noeuveglise M, et al. Among authors: penel n. BMC Cancer. 2024 Dec 18;24(1):1550. doi: 10.1186/s12885-024-13243-0. BMC Cancer. 2024. PMID: 39696086 Free PMC article.
Active surveillance in patients with extra-abdominal desmoid-type fibromatosis: a pooled analysis of three prospective observational studies.
Colombo C, Hakkesteegt S, Le Cesne A, Barretta F, Blay JY, Grünhagen DJ, Penel N, Lam L, Fiore M, Palassini E, Grignani G, Tolomeo F, Collini P, Merlini A, Perrone F, Stacchiotti S, Verhoef C, Bonvalot S, Gronchi A. Colombo C, et al. Among authors: penel n. Clin Cancer Res. 2024 Dec 2. doi: 10.1158/1078-0432.CCR-24-2340. Online ahead of print. Clin Cancer Res. 2024. PMID: 39620931
456 results