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Production of large, defined genome modifications in rats by targeting rat embryonic stem cells.
Lee J, Wang J, Ally R, Trzaska S, Hickey J, Mujica A, Miloscio L, Mastaitis J, Morse B, Smith J, Atanasio A, Chiao E, Chen H, Latuszek A, Hu Y, Valenzuela D, Romano C, Zambrowicz B, Auerbach W. Lee J, et al. Among authors: romano c. Stem Cell Reports. 2023 Jan 10;18(1):394-409. doi: 10.1016/j.stemcr.2022.11.012. Epub 2022 Dec 15. Stem Cell Reports. 2023. PMID: 36525967 Free PMC article.
Inhibition of complement pathway activation with Pozelimab, a fully human antibody to complement component C5.
Latuszek A, Liu Y, Olsen O, Foster R, Cao M, Lovric I, Yuan M, Liu N, Chen H, Zhang Q, Xiao H, Springer C, Ehrlich G, Kamat V, Rafique A, Hu Y, Krueger P, Huang T, Poueymirou W, Babb R, Rosconi MP, Retter MW, Chen G, Morton L, Zambrowicz B, Cao J, Romano C, Olson WC. Latuszek A, et al. Among authors: romano c. PLoS One. 2020 May 8;15(5):e0231892. doi: 10.1371/journal.pone.0231892. eCollection 2020. PLoS One. 2020. PMID: 32384086 Free PMC article.
Molecular taxonomy of human ocular outflow tissues defined by single-cell transcriptomics.
Patel G, Fury W, Yang H, Gomez-Caraballo M, Bai Y, Yang T, Adler C, Wei Y, Ni M, Schmitt H, Hu Y, Yancopoulos G, Stamer WD, Romano C. Patel G, et al. Among authors: romano c. Proc Natl Acad Sci U S A. 2020 Jun 9;117(23):12856-12867. doi: 10.1073/pnas.2001896117. Epub 2020 May 21. Proc Natl Acad Sci U S A. 2020. PMID: 32439707 Free PMC article.
ANGPTL7, a therapeutic target for increased intraocular pressure and glaucoma.
Praveen K, Patel GC, Gurski L, Ayer AH, Persaud T, Still MD, Miloscio L, Van Zyl T, Di Gioia SA, Brumpton B, Krebs K, Åsvold BO, Chen E, Chavali VRM, Fury W, Gudiseva HV, Hyde S, Jorgenson E, Lefebvre S, Li D, Li A, Mclninch J, Patel B, Rabinowitz JS, Salowe R, Schurmann C, Seidelin AS, Stahl E, Sun D, Teslovich TM, Tybjærg-Hansen A, Willer C, Waldron S, Walley S, Yang H, Zaveri S; Regeneron Genetics Center; GHS-RGC DiscovEHR Collaboration; Estonian Biobank Research Team; Hu Y, Hveem K, Melander O, Milani L, Stender S, O'Brien JM, Jones MB, Abecasis GR, Cantor MN, Weyne J, Karalis K, Economides A, Della Gatta G, Ferreira MA, Yancopoulos GD, Baras A, Romano C, Coppola G. Praveen K, et al. Among authors: romano c. Commun Biol. 2022 Oct 3;5(1):1051. doi: 10.1038/s42003-022-03932-6. Commun Biol. 2022. PMID: 36192519 Free PMC article.
A large meta-analysis identifies genes associated with anterior uveitis.
Gelfman S, Moscati A, Huergo SM, Wang R, Rajagopal V, Parikshak N, Pounraja VK, Chen E, Leblanc M, Hazlewood R, Freudenberg J, Cooper B, Ligocki AJ, Miller CG, Van Zyl T, Weyne J, Romano C, Sagdullaev B, Melander O, Baras A; Regeneron Genetics Center; Stahl EA, Coppola G. Gelfman S, et al. Among authors: romano c. Nat Commun. 2023 Nov 11;14(1):7300. doi: 10.1038/s41467-023-43036-1. Nat Commun. 2023. PMID: 37949852 Free PMC article.
Retinoschisin Deficiency Induces Persistent Aberrant Waves of Activity Affecting Neuroglial Signaling in the Retina.
Eleftheriou CG, Corona C, Khattak S, Alam NM, Ivanova E, Bianchimano P, Liu Y, Sun D, Singh R, Batoki JC, Prusky GT, McAnany JJ, Peachey NS, Romano C, Sagdullaev BT. Eleftheriou CG, et al. Among authors: romano c. J Neurosci. 2022 Sep 7;42(36):6983-7000. doi: 10.1523/JNEUROSCI.2128-21.2022. J Neurosci. 2022. PMID: 35906066 Free PMC article.
1,854 results