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Macrophage inflammatory and regenerative response periodicity is programmed by cell cycle and chromatin state.
Daniel B, Belk JA, Meier SL, Chen AY, Sandor K, Czimmerer Z, Varga Z, Bene K, Buquicchio FA, Qi Y, Kitano H, Wheeler JR, Foster DS, Januszyk M, Longaker MT, Chang HY, Satpathy AT. Daniel B, et al. Among authors: varga z. Mol Cell. 2023 Jan 5;83(1):121-138.e7. doi: 10.1016/j.molcel.2022.11.017. Epub 2022 Dec 14. Mol Cell. 2023. PMID: 36521490 Free PMC article.
The epigenetic state of IL-4-polarized macrophages enables inflammatory cistromic expansion and extended synergistic response to TLR ligands.
Czimmerer Z, Halasz L, Daniel B, Varga Z, Bene K, Domokos A, Hoeksema M, Shen Z, Berger WK, Cseh T, Jambrovics K, Kolostyak Z, Fenyvesi F, Varadi J, Poliska S, Hajas G, Szatmari I, Glass CK, Bacsi A, Nagy L. Czimmerer Z, et al. Among authors: varga z. Immunity. 2022 Nov 8;55(11):2006-2026.e6. doi: 10.1016/j.immuni.2022.10.004. Epub 2022 Nov 1. Immunity. 2022. PMID: 36323312 Free PMC article.
The transcriptional control of the VEGFA-VEGFR1 (FLT1) axis in alternatively polarized murine and human macrophages.
Domokos A, Varga Z, Jambrovics K, Caballero-Sánchez N, Szabo E, Nagy G, Scholtz B, Halasz L, Varadi E, Bene KP, Mazlo A, Bacsi A, Jeney V, Szebeni GJ, Nagy L, Czimmerer Z. Domokos A, et al. Among authors: varga z. Front Immunol. 2023 May 4;14:1168635. doi: 10.3389/fimmu.2023.1168635. eCollection 2023. Front Immunol. 2023. PMID: 37215144 Free PMC article.
EGR2 is an epigenomic regulator of phagocytosis and antifungal immunity in alveolar macrophages.
Kolostyak Z, Bojcsuk D, Baksa V, Szigeti ZM, Bene K, Czimmerer Z, Boto P, Fadel L, Poliska S, Halasz L, Tzerpos P, Berger WK, Villabona-Rueda A, Varga Z, Kovacs T, Patsalos A, Pap A, Vamosi G, Bai P, Dezso B, Spite M, D'Alessio FR, Szatmari I, Nagy L. Kolostyak Z, et al. Among authors: varga z. JCI Insight. 2024 Sep 10;9(17):e164009. doi: 10.1172/jci.insight.164009. JCI Insight. 2024. PMID: 39042472 Free PMC article.
1,115 results