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Nasal administration of anti-CD3 monoclonal antibody modulates effector CD8+ T cell function and induces a regulatory response in T cells in human subjects.
Chitnis T, Kaskow BJ, Case J, Hanus K, Li Z, Varghese JF, Healy BC, Gauthier C, Saraceno TJ, Saxena S, Lokhande H, Moreira TG, Zurawski J, Roditi RE, Bergmark RW, Giovannoni F, Torti MF, Li Z, Quintana F, Clementi WA, Shailubhai K, Weiner HL, Baecher-Allan CM. Chitnis T, et al. Among authors: li z. Front Immunol. 2022 Nov 23;13:956907. doi: 10.3389/fimmu.2022.956907. eCollection 2022. Front Immunol. 2022. PMID: 36505477 Free PMC article.
AHR is a Zika virus host factor and a candidate target for antiviral therapy.
Giovannoni F, Bosch I, Polonio CM, Torti MF, Wheeler MA, Li Z, Romorini L, Rodriguez Varela MS, Rothhammer V, Barroso A, Tjon EC, Sanmarco LM, Takenaka MC, Modaresi SMS, Gutiérrez-Vázquez C, Zanluqui NG, Dos Santos NB, Munhoz CD, Wang Z, Damonte EB, Sherr D, Gehrke L, Peron JPS, Garcia CC, Quintana FJ. Giovannoni F, et al. Among authors: li z. Nat Neurosci. 2020 Aug;23(8):939-951. doi: 10.1038/s41593-020-0664-0. Epub 2020 Jul 20. Nat Neurosci. 2020. PMID: 32690969 Free PMC article.
A potential role for AHR in SARS-CoV-2 pathology.
Giovannoni F, Li Z, Garcia CC, Quintana FJ. Giovannoni F, et al. Among authors: li z. Res Sq [Preprint]. 2020 Apr 27:rs.3.rs-25639. doi: 10.21203/rs.3.rs-25639/v1. Res Sq. 2020. PMID: 32702728 Free PMC article. Preprint.
Author Correction: AHR is a Zika virus host factor and a candidate target for antiviral therapy.
Giovannoni F, Bosch I, Polonio CM, Torti MF, Wheeler MA, Li Z, Romorini L, Rodriguez Varela MS, Rothhammer V, Barroso A, Tjon EC, Sanmarco LM, Takenaka MC, Modaresi SMS, Gutiérrez-Vázquez C, Zanluqui NG, Dos Santos NB, Munhoz CD, Wang Z, Damonte EB, Sherr D, Gehrke L, Peron JPS, Garcia CC, Quintana FJ. Giovannoni F, et al. Among authors: li z. Nat Neurosci. 2020 Oct;23(10):1307. doi: 10.1038/s41593-020-0700-0. Nat Neurosci. 2020. PMID: 32778795
Tolerogenic nanoparticles suppress central nervous system inflammation.
Kenison JE, Jhaveri A, Li Z, Khadse N, Tjon E, Tezza S, Nowakowska D, Plasencia A, Stanton VP Jr, Sherr DH, Quintana FJ. Kenison JE, et al. Among authors: li z. Proc Natl Acad Sci U S A. 2020 Dec 15;117(50):32017-32028. doi: 10.1073/pnas.2016451117. Epub 2020 Nov 25. Proc Natl Acad Sci U S A. 2020. PMID: 33239445 Free PMC article.
Gut-licensed IFNγ+ NK cells drive LAMP1+TRAIL+ anti-inflammatory astrocytes.
Sanmarco LM, Wheeler MA, Gutiérrez-Vázquez C, Polonio CM, Linnerbauer M, Pinho-Ribeiro FA, Li Z, Giovannoni F, Batterman KV, Scalisi G, Zandee SEJ, Heck ES, Alsuwailm M, Rosene DL, Becher B, Chiu IM, Prat A, Quintana FJ. Sanmarco LM, et al. Among authors: li z. Nature. 2021 Feb;590(7846):473-479. doi: 10.1038/s41586-020-03116-4. Epub 2021 Jan 6. Nature. 2021. PMID: 33408417 Free PMC article.
Self-tunable engineered yeast probiotics for the treatment of inflammatory bowel disease.
Scott BM, Gutiérrez-Vázquez C, Sanmarco LM, da Silva Pereira JA, Li Z, Plasencia A, Hewson P, Cox LM, O'Brien M, Chen SK, Moraes-Vieira PM, Chang BSW, Peisajovich SG, Quintana FJ. Scott BM, et al. Among authors: li z. Nat Med. 2021 Jul;27(7):1212-1222. doi: 10.1038/s41591-021-01390-x. Epub 2021 Jun 28. Nat Med. 2021. PMID: 34183837
AHR signaling is induced by infection with coronaviruses.
Giovannoni F, Li Z, Remes-Lenicov F, Dávola ME, Elizalde M, Paletta A, Ashkar AA, Mossman KL, Dugour AV, Figueroa JM, Barquero AA, Ceballos A, Garcia CC, Quintana FJ. Giovannoni F, et al. Among authors: li z. Nat Commun. 2021 Aug 26;12(1):5148. doi: 10.1038/s41467-021-25412-x. Nat Commun. 2021. PMID: 34446714 Free PMC article.
Identification of environmental factors that promote intestinal inflammation.
Sanmarco LM, Chao CC, Wang YC, Kenison JE, Li Z, Rone JM, Rejano-Gordillo CM, Polonio CM, Gutierrez-Vazquez C, Piester G, Plasencia A, Li L, Giovannoni F, Lee HG, Faust Akl C, Wheeler MA, Mascanfroni I, Jaronen M, Alsuwailm M, Hewson P, Yeste A, Andersen BM, Franks DG, Huang CJ, Ekwudo M, Tjon EC, Rothhammer V, Takenaka M, de Lima KA, Linnerbauer M, Guo L, Covacu R, Queva H, Fonseca-Castro PH, Bladi MA, Cox LM, Hodgetts KJ, Hahn ME, Mildner A, Korzenik J, Hauser R, Snapper SB, Quintana FJ. Sanmarco LM, et al. Among authors: li z, li l. Nature. 2022 Nov;611(7937):801-809. doi: 10.1038/s41586-022-05308-6. Epub 2022 Oct 20. Nature. 2022. PMID: 36266581 Free PMC article.
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