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Existing drugs as broad-spectrum and potent inhibitors for Zika virus by targeting NS2B-NS3 interaction.
Li Z, Brecher M, Deng YQ, Zhang J, Sakamuru S, Liu B, Huang R, Koetzner CA, Allen CA, Jones SA, Chen H, Zhang NN, Tian M, Gao F, Lin Q, Banavali N, Zhou J, Boles N, Xia M, Kramer LD, Qin CF, Li H. Li Z, et al. Among authors: koetzner ca. Cell Res. 2017 Aug;27(8):1046-1064. doi: 10.1038/cr.2017.88. Epub 2017 Jul 7. Cell Res. 2017. PMID: 28685770 Free PMC article.
Glycosaminoglycan Compositional Analysis of Relevant Tissues in Zika Virus Pathogenesis and in Vitro Evaluation of Heparin as an Antiviral against Zika Virus Infection.
Kim SY, Koetzner CA, Payne AF, Nierode GJ, Yu Y, Wang R, Barr E, Dordick JS, Kramer LD, Zhang F, Linhardt RJ. Kim SY, et al. Among authors: koetzner ca. Biochemistry. 2019 Feb 26;58(8):1155-1166. doi: 10.1021/acs.biochem.8b01267. Epub 2019 Feb 13. Biochemistry. 2019. PMID: 30698412 Free PMC article.
JMX0207, a Niclosamide Derivative with Improved Pharmacokinetics, Suppresses Zika Virus Infection Both In Vitro and In Vivo.
Li Z, Xu J, Lang Y, Fan X, Kuo L, D'Brant L, Hu S, Samrat SK, Trudeau N, Tharappel AM, Rugenstein N, Koetzner CA, Zhang J, Chen H, Kramer LD, Butler D, Zhang QY, Zhou J, Li H. Li Z, et al. Among authors: koetzner ca. ACS Infect Dis. 2020 Oct 9;6(10):2616-2628. doi: 10.1021/acsinfecdis.0c00217. Epub 2020 Sep 21. ACS Infect Dis. 2020. PMID: 32866370 Free PMC article.
Methylene blue is a potent and broad-spectrum inhibitor against Zika virus in vitro and in vivo.
Li Z, Lang Y, Sakamuru S, Samrat S, Trudeau N, Kuo L, Rugenstein N, Tharappel A, D'Brant L, Koetzner CA, Hu S, Zhang J, Huang R, Kramer LD, Butler D, Xia M, Li H. Li Z, et al. Among authors: koetzner ca. Emerg Microbes Infect. 2020 Dec;9(1):2404-2416. doi: 10.1080/22221751.2020.1838954. Emerg Microbes Infect. 2020. PMID: 33078696 Free PMC article.
Heartland Virus Transmission, Suffolk County, New York, USA.
Dupuis AP 2nd, Prusinski MA, O'Connor C, Maffei JG, Ngo KA, Koetzner CA, Santoriello MP, Romano CL, Xu G, Ribbe F, Campbell SR, Rich SM, Backenson PB, Kramer LD, Ciota AT. Dupuis AP 2nd, et al. Among authors: koetzner ca. Emerg Infect Dis. 2021 Dec;27(12):3128-3132. doi: 10.3201/eid2712.211426. Epub 2021 Oct 14. Emerg Infect Dis. 2021. PMID: 34648421 Free PMC article.
36 results