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Causal inference in medical records and complementary systems pharmacology for metformin drug repurposing towards dementia.
Charpignon ML, Vakulenko-Lagun B, Zheng B, Magdamo C, Su B, Evans K, Rodriguez S, Sokolov A, Boswell S, Sheu YH, Somai M, Middleton L, Hyman BT, Betensky RA, Finkelstein SN, Welsch RE, Tzoulaki I, Blacker D, Das S, Albers MW. Charpignon ML, et al. Among authors: hyman bt. Nat Commun. 2022 Dec 10;13(1):7652. doi: 10.1038/s41467-022-35157-w. Nat Commun. 2022. PMID: 36496454 Free PMC article.
Alpha-2 macroglobulin is genetically associated with Alzheimer disease.
Blacker D, Wilcox MA, Laird NM, Rodes L, Horvath SM, Go RC, Perry R, Watson B Jr, Bassett SS, McInnis MG, Albert MS, Hyman BT, Tanzi RE. Blacker D, et al. Among authors: hyman bt. Nat Genet. 1998 Aug;19(4):357-60. doi: 10.1038/1243. Nat Genet. 1998. PMID: 9697696
The cortical signature of Alzheimer's disease: regionally specific cortical thinning relates to symptom severity in very mild to mild AD dementia and is detectable in asymptomatic amyloid-positive individuals.
Dickerson BC, Bakkour A, Salat DH, Feczko E, Pacheco J, Greve DN, Grodstein F, Wright CI, Blacker D, Rosas HD, Sperling RA, Atri A, Growdon JH, Hyman BT, Morris JC, Fischl B, Buckner RL. Dickerson BC, et al. Among authors: hyman bt. Cereb Cortex. 2009 Mar;19(3):497-510. doi: 10.1093/cercor/bhn113. Epub 2008 Jul 16. Cereb Cortex. 2009. PMID: 18632739 Free PMC article.
830 results