Toti KS - Search Results

1

Novel alendronate-CGS21680 conjugate reduces bone resorption and induces new bone formation in post-menopausal osteoporosis and inflammatory osteolysis mouse models.

Larrañaga-Vera A, Toti KS, Flatow JS, Haraczy AJ, Warnick E, Rao H, Gao ZG, Sussman SM, Mediero A, Leucht P, Jacobson KA, Cronstein BN. Larrañaga-Vera A, et al. Among authors: toti ks. Arthritis Res Ther. 2022 Dec 9;24(1):265. doi: 10.1186/s13075-022-02961-0. Arthritis Res Ther. 2022. PMID: 36494860 Free PMC article.

2

Allosteric Antagonism of the A_2A Adenosine Receptor by a Series of Bitopic Ligands.

Gao ZG, Toti KS, Campbell R, Suresh RR, Yang H, Jacobson KA. Gao ZG, et al. Among authors: toti ks. Cells. 2020 May 12;9(5):1200. doi: 10.3390/cells9051200. Cells. 2020. PMID: 32408534 Free PMC article.

3

Fluorescent A_2A and A₃ adenosine receptor antagonists as flow cytometry probes.

Toti KS, Campbell RG, Lee H, Salmaso V, Suresh RR, Gao ZG, Jacobson KA. Toti KS, et al. Purinergic Signal. 2023 Sep;19(3):565-578. doi: 10.1007/s11302-022-09873-3. Epub 2022 Jun 10. Purinergic Signal. 2023. PMID: 35687212 Free PMC article.

4

Synthesis and evaluation of N⁶-substituted apioadenosines as potential adenosine A₃ receptor modulators.

Toti KS, Moss SM, Paoletta S, Gao ZG, Jacobson KA, Van Calenbergh S. Toti KS, et al. Bioorg Med Chem. 2014 Aug 1;22(15):4257-68. doi: 10.1016/j.bmc.2014.05.036. Epub 2014 May 23. Bioorg Med Chem. 2014. PMID: 24931275 Free PMC article.

5

South (S)- and North (N)-Methanocarba-7-Deazaadenosine Analogues as Inhibitors of Human Adenosine Kinase.

Toti KS, Osborne D, Ciancetta A, Boison D, Jacobson KA. Toti KS, et al. J Med Chem. 2016 Jul 28;59(14):6860-77. doi: 10.1021/acs.jmedchem.6b00689. Epub 2016 Jul 13. J Med Chem. 2016. PMID: 27410258 Free PMC article.

6

Polypharmacology of conformationally locked methanocarba nucleosides.

Jacobson KA, Tosh DK, Toti KS, Ciancetta A. Jacobson KA, et al. Among authors: toti ks. Drug Discov Today. 2017 Dec;22(12):1782-1791. doi: 10.1016/j.drudis.2017.07.013. Epub 2017 Aug 3. Drug Discov Today. 2017. PMID: 28781163 Free PMC article. Review.

7

Synthesis and Effect of Conformationally Locked Carbocyclic Guanine Nucleotides on Dynamin.

Toti KS, Jimah JR, Salmaso V, Hinshaw JE, Jacobson KA. Toti KS, et al. Biomolecules. 2022 Apr 16;12(4):584. doi: 10.3390/biom12040584. Biomolecules. 2022. PMID: 35454173 Free PMC article.

8

Convergent synthesis of 2-thioether-substituted (N)-methanocarba-adenosines as purine receptor agonists.

Suresh RR, Poe RB, Lin B, Lv K, Campbell RG, Gao ZG, Liston TE, Toti KS, Jacobson KA. Suresh RR, et al. Among authors: toti ks. RSC Adv. 2021 Aug 11;11(44):27369-27380. doi: 10.1039/d1ra05096f. eCollection 2021 Aug 9. RSC Adv. 2021. PMID: 35480676 Free PMC article.

9

Identification of a New Heterocyclic Scaffold for Inhibitors of the Polo-Box Domain of Polo-like Kinase 1.

Alverez CN, Park JE, Toti KS, Xia Y, Krausz KW, Rai G, Bang JK, Gonzalez FJ, Jacobson KA, Lee KS. Alverez CN, et al. Among authors: toti ks. J Med Chem. 2020 Nov 25;63(22):14087-14117. doi: 10.1021/acs.jmedchem.0c01669. Epub 2020 Nov 11. J Med Chem. 2020. PMID: 33175530 Free PMC article.

10

Structure activity relationship of novel antiviral nucleosides against Enterovirus A71.

Tosh DK, Toti KS, Hurst BL, Julander JG, Jacobson KA. Tosh DK, et al. Among authors: toti ks. Bioorg Med Chem Lett. 2020 Dec 1;30(23):127599. doi: 10.1016/j.bmcl.2020.127599. Epub 2020 Oct 5. Bioorg Med Chem Lett. 2020. PMID: 33031923 Free PMC article.

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