Mandrup S - Search Results

1

Current challenges in understanding the role of enhancers in disease.

Zaugg JB, Sahlén P, Andersson R, Alberich-Jorda M, de Laat W, Deplancke B, Ferrer J, Mandrup S, Natoli G, Plewczynski D, Rada-Iglesias A, Spicuglia S. Zaugg JB, et al. Among authors: mandrup s. Nat Struct Mol Biol. 2022 Dec;29(12):1148-1158. doi: 10.1038/s41594-022-00896-3. Epub 2022 Dec 8. Nat Struct Mol Biol. 2022. PMID: 36482255 Review.

2

MED14 tethers mediator to the N-terminal domain of peroxisome proliferator-activated receptor gamma and is required for full transcriptional activity and adipogenesis.

Grøntved L, Madsen MS, Boergesen M, Roeder RG, Mandrup S. Grøntved L, et al. Among authors: mandrup s. Mol Cell Biol. 2010 May;30(9):2155-69. doi: 10.1128/MCB.01238-09. Epub 2010 Mar 1. Mol Cell Biol. 2010. PMID: 20194623 Free PMC article.

3

Acute TNF-induced repression of cell identity genes is mediated by NFκB-directed redistribution of cofactors from super-enhancers.

Schmidt SF, Larsen BD, Loft A, Nielsen R, Madsen JG, Mandrup S. Schmidt SF, et al. Among authors: mandrup s. Genome Res. 2015 Sep;25(9):1281-94. doi: 10.1101/gr.188300.114. Epub 2015 Jun 25. Genome Res. 2015. PMID: 26113076 Free PMC article.

4

Highly interconnected enhancer communities control lineage-determining genes in human mesenchymal stem cells.

Madsen JGS, Madsen MS, Rauch A, Traynor S, Van Hauwaert EL, Haakonsson AK, Javierre BM, Hyldahl M, Fraser P, Mandrup S. Madsen JGS, et al. Among authors: mandrup s. Nat Genet. 2020 Nov;52(11):1227-1238. doi: 10.1038/s41588-020-0709-z. Epub 2020 Oct 5. Nat Genet. 2020. PMID: 33020665

5

Transcriptional networks controlling stromal cell differentiation.

Rauch A, Mandrup S. Rauch A, et al. Among authors: mandrup s. Nat Rev Mol Cell Biol. 2021 Jul;22(7):465-482. doi: 10.1038/s41580-021-00357-7. Epub 2021 Apr 9. Nat Rev Mol Cell Biol. 2021. PMID: 33837369 Review.

6

Acyl-CoA-binding protein/diazepam-binding inhibitor gene and pseudogenes. A typical housekeeping gene family.

Mandrup S, Hummel R, Ravn S, Jensen G, Andreasen PH, Gregersen N, Knudsen J, Kristiansen K. Mandrup S, et al. J Mol Biol. 1992 Dec 5;228(3):1011-22. doi: 10.1016/0022-2836(92)90888-q. J Mol Biol. 1992. PMID: 1469708

7

The gene encoding acyl-CoA-binding protein is subject to metabolic regulation by both sterol regulatory element-binding protein and peroxisome proliferator-activated receptor alpha in hepatocytes.

Sandberg MB, Bloksgaard M, Duran-Sandoval D, Duval C, Staels B, Mandrup S. Sandberg MB, et al. Among authors: mandrup s. J Biol Chem. 2005 Feb 18;280(7):5258-66. doi: 10.1074/jbc.M407515200. Epub 2004 Dec 15. J Biol Chem. 2005. PMID: 15611101 Free article.

8

Peroxisome proliferator-activated receptor subtype- and cell-type-specific activation of genomic target genes upon adenoviral transgene delivery.

Nielsen R, Grøntved L, Stunnenberg HG, Mandrup S. Nielsen R, et al. Among authors: mandrup s. Mol Cell Biol. 2006 Aug;26(15):5698-714. doi: 10.1128/MCB.02266-05. Mol Cell Biol. 2006. PMID: 16847324 Free PMC article.

9

A novel intronic peroxisome proliferator-activated receptor gamma enhancer in the uncoupling protein (UCP) 3 gene as a regulator of both UCP2 and -3 expression in adipocytes.

Bugge A, Siersbaek M, Madsen MS, Göndör A, Rougier C, Mandrup S. Bugge A, et al. Among authors: mandrup s. J Biol Chem. 2010 Jun 4;285(23):17310-7. doi: 10.1074/jbc.M110.120584. Epub 2010 Apr 1. J Biol Chem. 2010. PMID: 20360005 Free PMC article.

10

Genome-wide profiling of peroxisome proliferator-activated receptor γ in primary epididymal, inguinal, and brown adipocytes reveals depot-selective binding correlated with gene expression.

Siersbæk MS, Loft A, Aagaard MM, Nielsen R, Schmidt SF, Petrovic N, Nedergaard J, Mandrup S. Siersbæk MS, et al. Among authors: mandrup s. Mol Cell Biol. 2012 Sep;32(17):3452-63. doi: 10.1128/MCB.00526-12. Epub 2012 Jun 25. Mol Cell Biol. 2012. PMID: 22733994 Free PMC article.

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