Dick A - Search Results

1

The discovery and design of novel HIV-1 capsid modulators and future perspectives.

Ding D, Xu S, Zhang X, Jiang X, Cocklin S, Dick A, Zhan P, Liu X. Ding D, et al. Among authors: dick a. Expert Opin Drug Discov. 2023 Jan;18(1):5-12. doi: 10.1080/17460441.2023.2157401. Epub 2022 Dec 15. Expert Opin Drug Discov. 2023. PMID: 36480372

2

Field-Based Affinity Optimization of a Novel Azabicyclohexane Scaffold HIV-1 Entry Inhibitor.

Meuser ME, Rashad AA, Ozorowski G, Dick A, Ward AB, Cocklin S. Meuser ME, et al. Among authors: dick a. Molecules. 2019 Apr 22;24(8):1581. doi: 10.3390/molecules24081581. Molecules. 2019. PMID: 31013646 Free PMC article.

3

Design, synthesis and structure-activity relationships of 4-phenyl-1H-1,2,3-triazole phenylalanine derivatives as novel HIV-1 capsid inhibitors with promising antiviral activities.

Sun L, Huang T, Dick A, Meuser ME, Zalloum WA, Chen CH, Ding X, Gao P, Cocklin S, Lee KH, Zhan P, Liu X. Sun L, et al. Among authors: dick a. Eur J Med Chem. 2020 Mar 15;190:112085. doi: 10.1016/j.ejmech.2020.112085. Epub 2020 Jan 24. Eur J Med Chem. 2020. PMID: 32066010 Free PMC article.

4

Discovery of novel 1,4-disubstituted 1,2,3-triazole phenylalanine derivatives as HIV-1 capsid inhibitors.

Jiang X, Wu G, Zalloum WA, Meuser ME, Dick A, Sun L, Chen CH, Kang D, Jing L, Jia R, Cocklin S, Lee KH, Liu X, Zhan P. Jiang X, et al. Among authors: dick a. RSC Adv. 2019;9(50):28961-28986. doi: 10.1039/c9ra05869a. Epub 2019 Sep 16. RSC Adv. 2019. PMID: 32089839 Free PMC article.

5

Bioisosteric Replacement as a Tool in Anti-HIV Drug Design.

Dick A, Cocklin S. Dick A, et al. Pharmaceuticals (Basel). 2020 Feb 28;13(3):36. doi: 10.3390/ph13030036. Pharmaceuticals (Basel). 2020. PMID: 32121077 Free PMC article. Review.

6

Recent Advances in HIV-1 Gag Inhibitor Design and Development.

Dick A, Cocklin S. Dick A, et al. Molecules. 2020 Apr 7;25(7):1687. doi: 10.3390/molecules25071687. Molecules. 2020. PMID: 32272714 Free PMC article. Review.

7

Design, Synthesis, and Mechanism Study of Benzenesulfonamide-Containing Phenylalanine Derivatives as Novel HIV-1 Capsid Inhibitors with Improved Antiviral Activities.

Sun L, Dick A, Meuser ME, Huang T, Zalloum WA, Chen CH, Cherukupalli S, Xu S, Ding X, Gao P, Kang D, De Clercq E, Pannecouque C, Cocklin S, Lee KH, Liu X, Zhan P. Sun L, et al. Among authors: dick a. J Med Chem. 2020 May 14;63(9):4790-4810. doi: 10.1021/acs.jmedchem.0c00015. Epub 2020 Apr 29. J Med Chem. 2020. PMID: 32298111 Free PMC article.

8

Inhibitors of SARS-CoV-2 Entry: Current and Future Opportunities.

Xiu S, Dick A, Ju H, Mirzaie S, Abdi F, Cocklin S, Zhan P, Liu X. Xiu S, et al. Among authors: dick a. J Med Chem. 2020 Nov 12;63(21):12256-12274. doi: 10.1021/acs.jmedchem.0c00502. Epub 2020 Jun 25. J Med Chem. 2020. PMID: 32539378 Free PMC article. Review.

9

Rapid Optimization of the Metabolic Stability of a Human Immunodeficiency Virus Type-1 Capsid Inhibitor Using a Multistep Computational Workflow.

Meuser ME, Reddy PAN, Dick A, Maurancy JM, Salvino JM, Cocklin S. Meuser ME, et al. Among authors: dick a. J Med Chem. 2021 Apr 8;64(7):3747-3766. doi: 10.1021/acs.jmedchem.0c01810. Epub 2021 Mar 22. J Med Chem. 2021. PMID: 33750123 Free PMC article.

10

New RAD51 Inhibitors to Target Homologous Recombination in Human Cells.

Shkundina IS, Gall AA, Dick A, Cocklin S, Mazin AV. Shkundina IS, et al. Among authors: dick a. Genes (Basel). 2021 Jun 16;12(6):920. doi: 10.3390/genes12060920. Genes (Basel). 2021. PMID: 34208492 Free PMC article.

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