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Page 1
Epithelial TGFβ engages growth-factor signalling to circumvent apoptosis and drive intestinal tumourigenesis with aggressive features.
Flanagan DJ, Amirkhah R, Vincent DF, Gunduz N, Gentaz P, Cammareri P, McCooey AJ, McCorry AMB, Fisher NC, Davis HL, Ridgway RA, Lohuis J, Leach JDG, Jackstadt R, Gilroy K, Mariella E, Nixon C, Clark W, Hedley A, Markert EK, Strathdee D, Bartholin L, Redmond KL, Kerr EM, Longley DB, Ginty F, Cho S, Coleman HG, Loughrey MB, Bardelli A, Maughan TS, Campbell AD, Lawler M, Leedham SJ, Barry ST, Inman GJ, van Rheenen J, Dunne PD, Sansom OJ. Flanagan DJ, et al. Among authors: lohuis j. Nat Commun. 2022 Dec 7;13(1):7551. doi: 10.1038/s41467-022-35134-3. Nat Commun. 2022. PMID: 36477656 Free PMC article.
Epithelial NOTCH Signaling Rewires the Tumor Microenvironment of Colorectal Cancer to Drive Poor-Prognosis Subtypes and Metastasis.
Jackstadt R, van Hooff SR, Leach JD, Cortes-Lavaud X, Lohuis JO, Ridgway RA, Wouters VM, Roper J, Kendall TJ, Roxburgh CS, Horgan PG, Nixon C, Nourse C, Gunzer M, Clark W, Hedley A, Yilmaz OH, Rashid M, Bailey P, Biankin AV, Campbell AD, Adams DJ, Barry ST, Steele CW, Medema JP, Sansom OJ. Jackstadt R, et al. Among authors: lohuis jo. Cancer Cell. 2019 Sep 16;36(3):319-336.e7. doi: 10.1016/j.ccell.2019.08.003. Cancer Cell. 2019. PMID: 31526760 Free PMC article.
Author Correction: Epithelial TGFβ engages growth-factor signalling to circumvent apoptosis and drive intestinal tumourigenesis with aggressive features.
Flanagan DJ, Amirkhah R, Vincent DF, Gunduz N, Gentaz P, Cammareri P, McCooey AJ, McCorry AMB, Fisher NC, Davis HL, Ridgway RA, Lohuis J, Leach JDG, Jackstadt R, Gilroy K, Mariella E, Nixon C, Clark W, Hedley A, Markert EK, Strathdee D, Bartholin L, Redmond KL, Kerr EM, Longley DB, Ginty F, Cho S, Coleman HG, Loughrey MB, Bardelli A, Maughan TS, Campbell AD, Lawler M, Leedham SJ, Barry ST, Inman GJ, van Rheenen J, Dunne PD, Sansom OJ. Flanagan DJ, et al. Among authors: lohuis j. Nat Commun. 2023 Jan 31;14(1):522. doi: 10.1038/s41467-023-36266-w. Nat Commun. 2023. PMID: 36720858 Free PMC article. No abstract available.
The oestrous cycle stage affects mammary tumour sensitivity to chemotherapy.
Bornes L, van Winden LJ, Geurts VCM, de Bruijn B, Azarang L, Lanfermeijer M, Caruso M, Proost N, Boeije M, Lohuis JO, Belthier G, Noguera Delgado E, de Gruil N, Kroep JR, van de Ven M, Menezes R, Wesseling J, Kok M, Linn S, Broeks A, van Rossum HH, Scheele CLGJ, van Rheenen J. Bornes L, et al. Among authors: lohuis jo. Nature. 2025 Jan;637(8044):195-204. doi: 10.1038/s41586-024-08276-1. Epub 2024 Dec 4. Nature. 2025. PMID: 39633046 Free PMC article.
Epithelial-to-Mesenchymal Transition Drives Invasiveness of Breast Cancer Brain Metastases.
Margarido AS, Uceda-Castro R, Hahn K, de Bruijn R, Kester L, Hofland I, Lohuis J, Seinstra D, Broeks A, Jonkers J, Broekman MLD, Wesseling P, Vennin C, Vizoso M, van Rheenen J. Margarido AS, et al. Among authors: lohuis j. Cancers (Basel). 2022 Jun 25;14(13):3115. doi: 10.3390/cancers14133115. Cancers (Basel). 2022. PMID: 35804890 Free PMC article.
Taxanes trigger cancer cell killing in vivo by inducing non-canonical T cell cytotoxicity.
Vennin C, Cattaneo CM, Bosch L, Vegna S, Ma X, Damstra HGJ, Martinovic M, Tsouri E, Ilic M, Azarang L, van Weering JRT, Pulver E, Zeeman AL, Schelfhorst T, Lohuis JO, Rios AC, Dekkers JF, Akkari L, Menezes R, Medema R, Baglio SR, Akhmanova A, Linn SC, Lemeer S, Pegtel DM, Voest EE, van Rheenen J. Vennin C, et al. Among authors: lohuis jo. Cancer Cell. 2023 Jun 12;41(6):1170-1185.e12. doi: 10.1016/j.ccell.2023.05.009. Cancer Cell. 2023. PMID: 37311414 Free article.
Bacterial complications of postpartum uterine involution in cattle.
Földi J, Kulcsár M, Pécsi A, Huyghe B, de Sa C, Lohuis JA, Cox P, Huszenicza G. Földi J, et al. Among authors: lohuis ja. Anim Reprod Sci. 2006 Dec;96(3-4):265-81. doi: 10.1016/j.anireprosci.2006.08.006. Epub 2006 Aug 3. Anim Reprod Sci. 2006. PMID: 16956738 Review.
Pharmacokinetics of ibafloxacin in healthy cats.
Coulet M, Morello C, Cox P, Lohuis J. Coulet M, et al. Among authors: lohuis j. J Vet Pharmacol Ther. 2005 Feb;28(1):37-44. doi: 10.1111/j.1365-2885.2004.00623.x. J Vet Pharmacol Ther. 2005. PMID: 15720513 Clinical Trial.
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