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Discovery and systematic characterization of risk variants and genes for coronary artery disease in over a million participants.
Aragam KG, Jiang T, Goel A, Kanoni S, Wolford BN, Atri DS, Weeks EM, Wang M, Hindy G, Zhou W, Grace C, Roselli C, Marston NA, Kamanu FK, Surakka I, Venegas LM, Sherliker P, Koyama S, Ishigaki K, Åsvold BO, Brown MR, Brumpton B, de Vries PS, Giannakopoulou O, Giardoglou P, Gudbjartsson DF, Güldener U, Haider SMI, Helgadottir A, Ibrahim M, Kastrati A, Kessler T, Kyriakou T, Konopka T, Li L, Ma L, Meitinger T, Mucha S, Munz M, Murgia F, Nielsen JB, Nöthen MM, Pang S, Reinberger T, Schnitzler G, Smedley D, Thorleifsson G, von Scheidt M, Ulirsch JC; Biobank Japan; EPIC-CVD; Arnar DO, Burtt NP, Costanzo MC, Flannick J, Ito K, Jang DK, Kamatani Y, Khera AV, Komuro I, Kullo IJ, Lotta LA, Nelson CP, Roberts R, Thorgeirsson G, Thorsteinsdottir U, Webb TR, Baras A, Björkegren JLM, Boerwinkle E, Dedoussis G, Holm H, Hveem K, Melander O, Morrison AC, Orho-Melander M, Rallidis LS, Ruusalepp A, Sabatine MS, Stefansson K, Zalloua P, Ellinor PT, Farrall M, Danesh J, Ruff CT, Finucane HK, Hopewell JC, Clarke R, Gupta RM, Erdmann J, Samani NJ, Schunkert H, Watkins H, Willer CJ, Deloukas P, Kathiresan S, Butterworth AS; CARDIoGRAMplusC4D Consortium. Aragam KG, et al. Among authors: li l. Nat Genet. 2022 Dec;54(12):1803-1815. doi: 10.1038/s41588-022-01233-6. Epub 2022 Dec 6. Nat Genet. 2022. PMID: 36474045 Free PMC article.
Cis-epistasis at the LPA locus and risk of cardiovascular diseases.
Zeng L, Moser S, Mirza-Schreiber N, Lamina C, Coassin S, Nelson CP, Annilo T, Franzén O, Kleber ME, Mack S, Andlauer TFM, Jiang B, Stiller B, Li L, Willenborg C, Munz M, Kessler T, Kastrati A, Laugwitz KL, Erdmann J, Moebus S, Nöthen MM, Peters A, Strauch K, Müller-Nurasyid M, Gieger C, Meitinger T, Steinhagen-Thiessen E, März W, Metspalu A, Björkegren JLM, Samani NJ, Kronenberg F, Müller-Myhsok B, Schunkert H. Zeng L, et al. Among authors: li l. Cardiovasc Res. 2022 Mar 16;118(4):1088-1102. doi: 10.1093/cvr/cvab136. Cardiovasc Res. 2022. PMID: 33878186 Free PMC article.
Vascular Tissue Specific miRNA Profiles Reveal Novel Correlations with Risk Factors in Coronary Artery Disease.
Neiburga KD, Vilne B, Bauer S, Bongiovanni D, Ziegler T, Lachmann M, Wengert S, Hawe JS, Güldener U, Westerlund AM, Li L, Pang S, Yang C, Saar K, Huebner N, Maegdefessel L, DigiMed Bayern Consortium, Lange R, Krane M, Schunkert H, von Scheidt M. Neiburga KD, et al. Among authors: li l. Biomolecules. 2021 Nov 12;11(11):1683. doi: 10.3390/biom11111683. Biomolecules. 2021. PMID: 34827683 Free PMC article.
Integrative Prioritization of Causal Genes for Coronary Artery Disease.
Hao K, Ermel R, Sukhavasi K, Cheng H, Ma L, Li L, Amadori L, Koplev S, Franzén O, d'Escamard V, Chandel N, Wolhuter K, Bryce NS, Venkata VRM, Miller CL, Ruusalepp A, Schunkert H, Björkegren JLM, Kovacic JC. Hao K, et al. Among authors: li l. Circ Genom Precis Med. 2022 Feb;15(1):e003365. doi: 10.1161/CIRCGEN.121.003365. Epub 2021 Dec 28. Circ Genom Precis Med. 2022. PMID: 34961328 Free PMC article.
Transcriptome-wide association study of coronary artery disease identifies novel susceptibility genes.
Li L, Chen Z, von Scheidt M, Li S, Steiner A, Güldener U, Koplev S, Ma A, Hao K, Pan C, Lusis AJ, Pang S, Kessler T, Ermel R, Sukhavasi K, Ruusalepp A, Gagneur J, Erdmann J, Kovacic JC, Björkegren JLM, Schunkert H. Li L, et al. Among authors: li s. Basic Res Cardiol. 2022 Feb 17;117(1):6. doi: 10.1007/s00395-022-00917-8. Basic Res Cardiol. 2022. PMID: 35175464 Free PMC article.
Publisher Correction: Transcriptome-wide association study of coronary artery disease identifies novel susceptibility genes.
Li L, Chen Z, von Scheidt M, Li S, Steiner A, Güldener U, Koplev S, Ma A, Hao K, Pan C, Lusis AJ, Pang S, Kessler T, Ermel R, Sukhavasi K, Ruusalepp A, Gagneur J, Erdmann J, Kovacic JC, Björkegren JLM, Schunkert H. Li L, et al. Among authors: li s. Basic Res Cardiol. 2022 Apr 5;117(1):19. doi: 10.1007/s00395-022-00923-w. Basic Res Cardiol. 2022. PMID: 35381883 Free PMC article. No abstract available.
Genetic and modifiable risk factors combine multiplicatively in common disease.
Pang S, Yengo L, Nelson CP, Bourier F, Zeng L, Li L, Kessler T, Erdmann J, Mägi R, Läll K, Metspalu A, Mueller-Myhsok B, Samani NJ, Visscher PM, Schunkert H. Pang S, et al. Among authors: li l. Clin Res Cardiol. 2023 Feb;112(2):247-257. doi: 10.1007/s00392-022-02081-4. Epub 2022 Aug 20. Clin Res Cardiol. 2023. PMID: 35987817 Free PMC article.
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