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Design and characterization of a heterobifunctional degrader of KEAP1.
Chen H, Nguyen NH, Magtoto CM, Cobbold SA, Bidgood GM, Meza Guzman LG, Richardson LW, Corbin J, Au AE, Lechtenberg BC, Feltham R, Sutherland KD, Grohmann C, Nicholson SE, Sleebs BE. Chen H, et al. Among authors: nguyen nh. Redox Biol. 2023 Feb;59:102552. doi: 10.1016/j.redox.2022.102552. Epub 2022 Nov 26. Redox Biol. 2023. PMID: 36473314 Free PMC article.
Property activity refinement of 2-anilino 4-amino substituted quinazolines as antimalarials with fast acting asexual parasite activity.
Ashton TD, Ngo A, Favuzza P, Bullen HE, Gancheva MR, Romeo O, Parkyn Schneider M, Nguyen N, Steel RWJ, Duffy S, Lowes KN, Sabroux HJ, Avery VM, Boddey JA, Wilson DW, Cowman AF, Gilson PR, Sleebs BE. Ashton TD, et al. Bioorg Chem. 2021 Dec;117:105359. doi: 10.1016/j.bioorg.2021.105359. Epub 2021 Sep 21. Bioorg Chem. 2021. PMID: 34689083
Structure-activity relationship and target investigation of 2-aryl quinolines with nematocidal activity.
Shanley HT, Taki AC, Nguyen N, Wang T, Byrne JJ, Ang CS, Leeming MG, Nie S, Williamson N, Zheng Y, Young ND, Korhonen PK, Hofmann A, Chang BCH, Wells TNC, Häberli C, Keiser J, Jabbar A, Sleebs BE, Gasser RB. Shanley HT, et al. Int J Parasitol Drugs Drug Resist. 2024 Apr;24:100522. doi: 10.1016/j.ijpddr.2024.100522. Epub 2024 Jan 23. Int J Parasitol Drugs Drug Resist. 2024. PMID: 38295619 Free PMC article.
614 results