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Identification, binding, and structural characterization of single domain anti-PD-L1 antibodies inhibitory of immune regulatory proteins PD-1 and CD80.
Kang-Pettinger T, Walker K, Brown R, Cowan R, Wright H, Baravalle R, Waters LC, Muskett FW, Bowler MW, Sawmynaden K, Coombs PJ, Carr MD, Hall G. Kang-Pettinger T, et al. Among authors: brown r. J Biol Chem. 2023 Jan;299(1):102769. doi: 10.1016/j.jbc.2022.102769. Epub 2022 Dec 5. J Biol Chem. 2023. PMID: 36470427 Free PMC article.
Cross-Reactive SARS-CoV-2 Neutralizing Antibodies From Deep Mining of Early Patient Responses.
Bullen G, Galson JD, Hall G, Villar P, Moreels L, Ledsgaard L, Mattiuzzo G, Bentley EM, Masters EW, Tang D, Millett S, Tongue D, Brown R, Diamantopoulos I, Parthiban K, Tebbutt C, Leah R, Chaitanya K, Ergueta-Carballo S, Pazeraitis D, Surade SB, Ashiru O, Crippa L, Cowan R, Bowler MW, Campbell JI, Lee WJ, Carr MD, Matthews D, Pfeffer P, Hufton SE, Sawmynaden K, Osbourn J, McCafferty J, Karatt-Vellatt A. Bullen G, et al. Among authors: brown r. Front Immunol. 2021 Jun 15;12:678570. doi: 10.3389/fimmu.2021.678570. eCollection 2021. Front Immunol. 2021. PMID: 34211469 Free PMC article.
An antagonistic monoclonal anti-Plexin-B1 antibody exerts therapeutic effects in mouse models of postmenopausal osteoporosis and multiple sclerosis.
Vogler M, Oleksy A, Schulze S, Fedorova M, Kojonazarov B, Nijjar S, Patel S, Jossi S, Sawmynaden K, Henry M, Brown R, Matthews D, Offermanns S, Worzfeld T. Vogler M, et al. Among authors: brown r. J Biol Chem. 2022 Sep;298(9):102265. doi: 10.1016/j.jbc.2022.102265. Epub 2022 Jul 15. J Biol Chem. 2022. PMID: 35850304 Free PMC article.
Complete humanization of the mouse immunoglobulin loci enables efficient therapeutic antibody discovery.
Lee EC, Liang Q, Ali H, Bayliss L, Beasley A, Bloomfield-Gerdes T, Bonoli L, Brown R, Campbell J, Carpenter A, Chalk S, Davis A, England N, Fane-Dremucheva A, Franz B, Germaschewski V, Holmes H, Holmes S, Kirby I, Kosmac M, Legent A, Lui H, Manin A, O'Leary S, Paterson J, Sciarrillo R, Speak A, Spensberger D, Tuffery L, Waddell N, Wang W, Wells S, Wong V, Wood A, Owen MJ, Friedrich GA, Bradley A. Lee EC, et al. Among authors: brown r. Nat Biotechnol. 2014 Apr;32(4):356-63. doi: 10.1038/nbt.2825. Epub 2014 Mar 16. Nat Biotechnol. 2014. PMID: 24633243
A Semi-Virtual Trier Social Stress Test (SV-TSST).
Miller M, Divine M, McAfee C, Brown R, Sears S, Krautkramer C, Gogia R, Josephs RA, Champagne FA. Miller M, et al. Among authors: brown r. Psychoneuroendocrinology. 2024 Dec 21;172:107267. doi: 10.1016/j.psyneuen.2024.107267. Online ahead of print. Psychoneuroendocrinology. 2024. PMID: 39724822
Impact of the CAPTURE COPD Screening Tool in US Primary Care: A Cluster Randomized Trial.
Martinez FJ, Yawn BP, Angulo D, Lopez C, Murray S, Mannino D, Anderson S, Dolor R, Elder N, Joo M, Khan I, Knox LM, Meldrum C, Peters E, Spino C, Tapp H, Thomashow B, Zittleman L, Brown R, Make B, Han MK; CAPTURE study group. Martinez FJ, et al. Among authors: brown r. Am J Respir Crit Care Med. 2024 Dec 23. doi: 10.1164/rccm.202405-0921OC. Online ahead of print. Am J Respir Crit Care Med. 2024. PMID: 39715575
Multilingual Research Strategies to Enhance Equity.
Brown R, Ortiz P, Berrigan L, Cullen D. Brown R, et al. JAMA Pediatr. 2024 Dec 23. doi: 10.1001/jamapediatrics.2024.5619. Online ahead of print. JAMA Pediatr. 2024. PMID: 39714859
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