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Preclinical and Clinical Pharmacokinetics and Bioavailability in Healthy Volunteers of a Novel Formulation of the Selective P2X3 Receptor Antagonist Eliapixant.
Francke K, Chattopadhyay N, Klein S, Rottmann A, Krickau D, van de Wetering J, Friedrich C. Francke K, et al. Among authors: van de wetering j. Eur J Drug Metab Pharmacokinet. 2023 Jan;48(1):75-87. doi: 10.1007/s13318-022-00805-5. Epub 2022 Dec 5. Eur J Drug Metab Pharmacokinet. 2023. PMID: 36469250 Clinical Trial.
The effect of mirabegron, a potent and selective β3-adrenoceptor agonist, on the pharmacokinetics of CYP2D6 substrates desipramine and metoprolol.
Krauwinkel W, Dickinson J, Schaddelee M, Meijer J, Tretter R, van de Wetering J, Strabach G, van Gelderen M. Krauwinkel W, et al. Among authors: van gelderen m, van de wetering j. Eur J Drug Metab Pharmacokinet. 2014 Mar;39(1):43-52. doi: 10.1007/s13318-013-0133-1. Epub 2013 Jun 1. Eur J Drug Metab Pharmacokinet. 2014. PMID: 23728524 Clinical Trial.
First-in-human study with ACT-1014-6470, a novel oral complement factor 5a receptor 1 (C5aR1) antagonist, supported by pharmacokinetic predictions from animals to patients.
Ort M, Dingemanse J, Hsin CH, Richard M, Huehn E, Sabattini G, van de Wetering J, Kornberger R, van den Anker J, Kaufmann P. Ort M, et al. Among authors: van de wetering j, van den anker j. Basic Clin Pharmacol Toxicol. 2022 Aug;131(2):114-128. doi: 10.1111/bcpt.13756. Epub 2022 Jun 8. Basic Clin Pharmacol Toxicol. 2022. PMID: 35596117 Free article. Clinical Trial.
Safety, pharmacokinetics, and pharmacodynamics of TV-1380, a novel mutated butyrylcholinesterase treatment for cocaine addiction, after single and multiple intramuscular injections in healthy subjects.
Cohen-Barak O, Wildeman J, van de Wetering J, Hettinga J, Schuilenga-Hut P, Gross A, Clark S, Bassan M, Gilgun-Sherki Y, Mendzelevski B, Spiegelstein O. Cohen-Barak O, et al. Among authors: van de wetering j. J Clin Pharmacol. 2015 May;55(5):573-83. doi: 10.1002/jcph.450. Epub 2015 Jan 12. J Clin Pharmacol. 2015. PMID: 25524052 Free PMC article. Clinical Trial.
Kidney Transplant Outcome Following Donation After Euthanasia.
Slagter JS, Kimenai HJAN, van de Wetering J, Hagenaars HJAM, Reinders MEJ, Polak WG, Porte RJ, Minnee RC. Slagter JS, et al. Among authors: van de wetering j. JAMA Surg. 2024 Dec 1;159(12):1347-1353. doi: 10.1001/jamasurg.2024.3913. JAMA Surg. 2024. PMID: 39320864
Anti-HLA Class II Antibodies Are the Most Resistant to Desensitization in Crossmatch-positive Living-donor Kidney Transplantations: A Patient Series.
de Weerd AE, Roelen DL, Betjes MGH, Clahsen-van Groningen MC, Haasnoot GW, Kho MML, Reinders MEJ, Roodnat JI, Severs D, Karahan GE, van de Wetering J. de Weerd AE, et al. Among authors: van de wetering j. Transplant Direct. 2024 Aug 29;10(9):e1695. doi: 10.1097/TXD.0000000000001695. eCollection 2024 Sep. Transplant Direct. 2024. PMID: 39220218 Free PMC article.
Delayed Graft Function After Kidney Transplantation: The Role of Residual Diuresis and Waste Products, as Oxalic Acid and Its Precursors.
Post Hospers G, Visser WJ, Verhoeven JGHP, Laging M, Baart SJ, Mertens Zur Borg IRAM, Hesselink DA, de Mik-van Egmond AME, Betjes MGH, van Agteren M, Severs D, van de Wetering J, Zietse R, Vos MJ, Kema IP, Kho MML, Reinders MEJ, Roodnat JI. Post Hospers G, et al. Among authors: van de wetering j. Transpl Int. 2024 Jul 19;37:13218. doi: 10.3389/ti.2024.13218. eCollection 2024. Transpl Int. 2024. PMID: 39100754 Free PMC article.
132 results