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An orally available small molecule that targets soluble TNF to deliver anti-TNF biologic-like efficacy in rheumatoid arthritis.
Vugler A, O'Connell J, Nguyen MA, Weitz D, Leeuw T, Hickford E, Verbitsky A, Ying X, Rehberg M, Carrington B, Merriman M, Moss A, Nicholas JM, Stanley P, Wright S, Bourne T, Foricher Y, Brookings D, Horsley H, Herrmann M, Rao S, Kohlmann M, Florian P. Vugler A, et al. Among authors: nguyen ma. Front Pharmacol. 2022 Nov 16;13:1037983. doi: 10.3389/fphar.2022.1037983. eCollection 2022. Front Pharmacol. 2022. PMID: 36467083 Free PMC article.
Non-Labeled, Stable Labeled, or Radiolabelled Approaches for Provision of Intravenous Pharmacokinetics in Humans: A Discussion Piece.
Young GC, Spracklin DK, James AD, Hvenegaard MG, Pedersen ML, Wagner DS, Georgi K, Schieferstein H, Bjornsdottir I, Romeo AA, Cassidy KC, Da-Violante G, Blech S, Schulz SI, Cuyckens F, Nguyen MA, Scarfe G. Young GC, et al. Among authors: nguyen ma. Clin Pharmacol Ther. 2024 May;115(5):931-938. doi: 10.1002/cpt.3121. Epub 2023 Dec 22. Clin Pharmacol Ther. 2024. PMID: 38018358 Review.
Scalable assessment of genome editing off-targets associated with genetic variants.
Lin J, Nguyen MA, Lin LY, Zeng J, Verma A, Neri NR, da Silva LF, Mucci A, Wolfe S, Shaw KL, Clement K, Brendel C, Pinello L, Pellin D, Bauer DE. Lin J, et al. Among authors: nguyen ma. bioRxiv [Preprint]. 2024 Jul 25:2024.07.24.605019. doi: 10.1101/2024.07.24.605019. bioRxiv. 2024. PMID: 39211178 Free PMC article. Preprint.
Unbiased discovery of cancer pathways and therapeutics using Pathway Ensemble Tool and Benchmark.
Wang L, Pattnaik A, Sahoo SS, Stone EG, Zhuang Y, Benton A, Tajmul M, Chakravorty S, Dhawan D, Nguyen MA, Sirit I, Mundy K, Ricketts CJ, Hadisurya M, Baral G, Tinsley SL, Anderson NL, Hoda S, Briggs SD, Kaimakliotis HZ, Allen-Petersen BL, Tao WA, Linehan WM, Knapp DW, Hanna JA, Olson MR, Afzali B, Kazemian M. Wang L, et al. Among authors: nguyen ma. Nat Commun. 2024 Aug 24;15(1):7288. doi: 10.1038/s41467-024-51859-9. Nat Commun. 2024. PMID: 39179644 Free PMC article.
168 results