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ELABELA Improves Cardio-Renal Outcome in Fatal Experimental Septic Shock.
Coquerel D, Chagnon F, Sainsily X, Dumont L, Murza A, Côté J, Dumaine R, Sarret P, Marsault É, Salvail D, Auger-Messier M, Lesur O. Coquerel D, et al. Crit Care Med. 2017 Nov;45(11):e1139-e1148. doi: 10.1097/CCM.0000000000002639. Crit Care Med. 2017. PMID: 28777197
A Systematic Exploration of Macrocyclization in Apelin-13: Impact on Binding, Signaling, Stability, and Cardiovascular Effects.
Trân K, Murza A, Sainsily X, Coquerel D, Côté J, Belleville K, Haroune L, Longpré JM, Dumaine R, Salvail D, Lesur O, Auger-Messier M, Sarret P, Marsault É. Trân K, et al. Among authors: coquerel d. J Med Chem. 2018 Mar 22;61(6):2266-2277. doi: 10.1021/acs.jmedchem.7b01353. Epub 2018 Feb 26. J Med Chem. 2018. PMID: 29461833
Elabela Protects Spontaneously Hypertensive Rats From Hypertension and Cardiorenal Dysfunctions Exacerbated by Dietary High-Salt Intake.
Sainsily X, Coquerel D, Giguère H, Dumont L, Tran K, Noll C, Ionescu AL, Côté J, Longpré JM, Carpentier A, Marsault É, Lesur O, Sarret P, Auger-Messier M. Sainsily X, et al. Among authors: coquerel d. Front Pharmacol. 2021 Jul 27;12:709467. doi: 10.3389/fphar.2021.709467. eCollection 2021. Front Pharmacol. 2021. PMID: 34385922 Free PMC article.
Size-Reduced Macrocyclic Analogues of [Pyr1]-apelin-13 Showing Negative Gα12 Bias Still Produce Prolonged Cardiac Effects.
Tran K, Sainsily X, Côté J, Coquerel D, Couvineau P, Saibi S, Haroune L, Besserer-Offroy É, Flynn-Robitaille J, Resua Rojas M, Murza A, Longpré JM, Auger-Messier M, Lesur O, Bouvier M, Marsault É, Boudreault PL, Sarret P. Tran K, et al. Among authors: coquerel d. J Med Chem. 2022 Jan 13;65(1):531-551. doi: 10.1021/acs.jmedchem.1c01708. Epub 2022 Jan 4. J Med Chem. 2022. PMID: 34982553
25 results