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Senescent cells suppress macrophage-mediated corpse removal via upregulation of the CD47-QPCT/L axis.
Schloesser D, Lindenthal L, Sauer J, Chung KJ, Chavakis T, Griesser E, Baskaran P, Maier-Habelsberger U, Fundel-Clemens K, Schlotthauer I, Watson CK, Swee LK, Igney F, Park JE, Huber-Lang MS, Thomas MJ, El Kasmi KC, Murray PJ. Schloesser D, et al. Among authors: el kasmi kc. J Cell Biol. 2023 Feb 6;222(2):e202207097. doi: 10.1083/jcb.202207097. Epub 2022 Dec 2. J Cell Biol. 2023. PMID: 36459066 Free PMC article.
Antifibrotic Drug Nintedanib Inhibits CSF1R to Promote IL-4-associated Tissue Repair Macrophages.
Watson CK, Schloesser D, Fundel-Clemens K, Lerner C, Gabler S, Baskaran P, Wohnhaas CT, Dichtl S, Huber HJ, Ask K, Gantner F, Viollet C, Thomas MJ, Ramirez F, Murray PJ, El Kasmi KC. Watson CK, et al. Among authors: el kasmi kc. Am J Respir Cell Mol Biol. 2023 Apr;68(4):366-380. doi: 10.1165/rcmb.2022-0021OC. Am J Respir Cell Mol Biol. 2023. PMID: 36227799
Lactate and IL6 define separable paths of inflammatory metabolic adaptation.
Dichtl S, Lindenthal L, Zeitler L, Behnke K, Schlösser D, Strobl B, Scheller J, El Kasmi KC, Murray PJ. Dichtl S, et al. Among authors: el kasmi kc. Sci Adv. 2021 Jun 23;7(26):eabg3505. doi: 10.1126/sciadv.abg3505. Print 2021 Jun. Sci Adv. 2021. PMID: 34162546 Free PMC article.
Gene-selective transcription promotes the inhibition of tissue reparative macrophages by TNF.
Dichtl S, Sanin DE, Koss CK, Willenborg S, Petzold A, Tanzer MC, Dahl A, Kabat AM, Lindenthal L, Zeitler L, Satzinger S, Strasser A, Mann M, Roers A, Eming SA, El Kasmi KC, Pearce EJ, Murray PJ. Dichtl S, et al. Among authors: el kasmi kc. Life Sci Alliance. 2022 Jan 13;5(4):e202101315. doi: 10.26508/lsa.202101315. Print 2022 Apr. Life Sci Alliance. 2022. PMID: 35027468 Free PMC article.
CD206+ tumor-associated macrophages cross-present tumor antigen and drive antitumor immunity.
Modak M, Mattes AK, Reiss D, Skronska-Wasek W, Langlois R, Sabarth N, Konopitzky R, Ramirez F, Lehr K, Mayr T, Kind D, Viollet C, Swee LK, Petschenka J, El Kasmi KC, Noessner E, Kitt K, Pflanz S. Modak M, et al. Among authors: el kasmi kc. JCI Insight. 2022 Jun 8;7(11):e155022. doi: 10.1172/jci.insight.155022. JCI Insight. 2022. PMID: 35503656 Free PMC article.
LAG-3 regulates plasmacytoid dendritic cell homeostasis.
Workman CJ, Wang Y, El Kasmi KC, Pardoll DM, Murray PJ, Drake CG, Vignali DA. Workman CJ, et al. Among authors: el kasmi kc. J Immunol. 2009 Feb 15;182(4):1885-91. doi: 10.4049/jimmunol.0800185. J Immunol. 2009. PMID: 19201841 Free PMC article.
The TLR2-MyD88-NOD2-RIPK2 signalling axis regulates a balanced pro-inflammatory and IL-10-mediated anti-inflammatory cytokine response to Gram-positive cell walls.
Moreira LO, El Kasmi KC, Smith AM, Finkelstein D, Fillon S, Kim YG, Núñez G, Tuomanen E, Murray PJ. Moreira LO, et al. Among authors: el kasmi kc. Cell Microbiol. 2008 Oct;10(10):2067-77. doi: 10.1111/j.1462-5822.2008.01189.x. Epub 2008 Jun 28. Cell Microbiol. 2008. PMID: 18549453 Free PMC article.
IL36 is a critical upstream amplifier of neutrophilic lung inflammation in mice.
Koss CK, Wohnhaas CT, Baker JR, Tilp C, Przibilla M, Lerner C, Frey S, Keck M, Williams CMM, Peter D, Ramanujam M, Fine J, Gantner F, Thomas M, Barnes PJ, Donnelly LE, El Kasmi KC. Koss CK, et al. Among authors: el kasmi kc. Commun Biol. 2021 Feb 8;4(1):172. doi: 10.1038/s42003-021-01703-3. Commun Biol. 2021. PMID: 33558616 Free PMC article.
64 results