Walker KD - Search Results

1

Redirecting tropane alkaloid metabolism reveals pyrrolidine alkaloid diversity in Atropa belladonna.

Parks HM, Cinelli MA, Bedewitz MA, Grabar JM, Hurney SM, Walker KD, Jones AD, Barry CS. Parks HM, et al. Among authors: walker kd. New Phytol. 2023 Mar;237(5):1810-1825. doi: 10.1111/nph.18651. Epub 2022 Dec 18. New Phytol. 2023. PMID: 36451537 Free PMC article.

2

Biocatalysis of precursors to new-generation SB-T-taxanes effective against paclitaxel-resistant cancer cells.

Al-Hilfi A, Walker KD. Al-Hilfi A, et al. Among authors: walker kd. Arch Biochem Biophys. 2022 Apr 15;719:109165. doi: 10.1016/j.abb.2022.109165. Epub 2022 Feb 25. Arch Biochem Biophys. 2022. PMID: 35227656

3

Identification and characterization of the missing phosphatase on the riboflavin biosynthesis pathway in Arabidopsis thaliana.

Sa N, Rawat R, Thornburg C, Walker KD, Roje S. Sa N, et al. Among authors: walker kd. Plant J. 2016 Dec;88(5):705-716. doi: 10.1111/tpj.13291. Epub 2016 Sep 17. Plant J. 2016. PMID: 27490826 Free article.

4

CoA recycling by a benzoate coenzyme A ligase in cascade reactions with aroyltransferases to biocatalyze paclitaxel analogs.

Sullivan SA, Nawarathne IN, Walker KD. Sullivan SA, et al. Among authors: walker kd. Arch Biochem Biophys. 2020 Apr 15;683:108276. doi: 10.1016/j.abb.2020.108276. Epub 2020 Jan 21. Arch Biochem Biophys. 2020. PMID: 31978400

5

Mg²⁺-Ion Dependence Revealed for a BAHD 13-O-β-Aminoacyltransferase from Taxus Plants.

Al-Hilfi A, Li Z, Merz KM Jr, Walker KD. Al-Hilfi A, et al. Among authors: walker kd. JACS Au. 2024 Sep 30;4(11):4249-4262. doi: 10.1021/jacsau.4c00577. eCollection 2024 Nov 25. JACS Au. 2024. PMID: 39610752 Free PMC article.

6

Mutation of Aryl Binding Pocket Residues Results in an Unexpected Activity Switch in an Oryza sativa Tyrosine Aminomutase.

Walter T, Wijewardena D, Walker KD. Walter T, et al. Among authors: walker kd. Biochemistry. 2016 Jun 28;55(25):3497-503. doi: 10.1021/acs.biochem.6b00331. Epub 2016 Jun 14. Biochemistry. 2016. PMID: 27243642 No abstract available.

7

Paclitaxel Biosynthesis: Adenylation and Thiolation Domains of an NRPS TycA PheAT Module Produce Various Arylisoserine CoA Thioesters.

Muchiri R, Walker KD. Muchiri R, et al. Among authors: walker kd. Biochemistry. 2017 Mar 14;56(10):1415-1425. doi: 10.1021/acs.biochem.6b01188. Epub 2017 Mar 2. Biochemistry. 2017. PMID: 28230972

8

Biocatalysis of a Paclitaxel Analogue: Conversion of Baccatin III to N-Debenzoyl-N-(2-furoyl)paclitaxel and Characterization of an Amino Phenylpropanoyl CoA Transferase.

Thornburg CK, Walter T, Walker KD. Thornburg CK, et al. Among authors: walker kd. Biochemistry. 2017 Nov 7;56(44):5920-5930. doi: 10.1021/acs.biochem.7b00912. Biochemistry. 2017. PMID: 29068219

9

Insights into the mechanistic pathway of the Pantoea agglomerans phenylalanine aminomutase.

Strom S, Wanninayake U, Ratnayake ND, Walker KD, Geiger JH. Strom S, et al. Among authors: walker kd. Angew Chem Int Ed Engl. 2012 Mar 19;51(12):2898-902. doi: 10.1002/anie.201108525. Epub 2012 Feb 8. Angew Chem Int Ed Engl. 2012. PMID: 22319000 No abstract available.

10

A bacterial tyrosine aminomutase proceeds through retention or inversion of stereochemistry to catalyze its isomerization reaction.

Wanninayake U, Walker KD. Wanninayake U, et al. Among authors: walker kd. J Am Chem Soc. 2013 Jul 31;135(30):11193-204. doi: 10.1021/ja403918w. Epub 2013 Jul 16. J Am Chem Soc. 2013. PMID: 23800193

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